No subject
Wed Jan 20 18:08:02 PST 2016
hose interested in the nuts and bolts of diffraction methods. It is also a =
unique opportunity to meet many of the key members of the field. It is a fr=
iendly and productive conference, and an exciting one in terms of getting a=
preview of the future. We encourage you to attend, take part in great scie=
nce, and also interact in a less formal social and sometimes sporting atmos=
phere.
This will also be the second year that a related Gordon Research Seminar (G=
RS) is run. This is a meeting organized for and by post-docs and graduate s=
tudents. Drs. Rike Mueller-Werkmeister and Bradely Hintze are organizing t=
his with details at https://www.grc.org/programs.aspx?id=3D16486. We strong=
ly encourage laboratories with an interest in Diffraction Methods in Struct=
ural Biology to support their students in attending both the GRS and the GR=
C with the GRS serving as a useful introduction to the larger conference.
We are still raising funds for the GRS and GRC, in particular to enable you=
nger scientists to attend. We are grateful and thank those who have support=
ed us so far, and also those that are in the process of doing so. We are ac=
tively looking for further sponsorship.
Summer is a full time for meetings but this is going to be a very worthwhil=
e one. Please pass this onto interested colleagues.
Thanks,
Eddie and Arwen
Sunday 17th of July
Keynote Session: Structure and Dynamics
Discussion Leader: Elspeth Garman (University of Oxford, United Kingdom)
* Carrie Wilmot (University of Minnesota, USA) MauG Catalysis: =
A Tale of Ferryl Heme, Radicals and Long-Distance Hopping
* Joseph Ferrara (Rigaku Americas Corporation, USA) A special t=
alk to look back over 40 years of this GRC and describe the developments in=
the field since the first Diffraction Methods Meeting.
Monday 18th July
New Instruments and Opportunities
Discussion Leader: Sean McSweeny (NSLS-II, USA)
* Armin Wagner (Diamond Light Source, United Kingdom) In-Vacuum=
Long-Wavelength Crystallography - First Results
* Matthew Bowler (Synchrotron Crystallography Group, France) Fu=
lly Automatic Characterization and Data Collection: A New Tool for Structur=
al Biologist
* Marjolein Thunnissen (MAX IV Laboratory, Sweden) Possibilitie=
s for Structural and Dynamical Studies on Proteins at MAX IV
* Esko Oskanen (European Spallation Source, Sweden) Structural =
Biology with Neutrons - Opportunities at the European Spallation Source
* William Graves (Arizona State University) Electron Diffractio=
n as a Method to Produce a Tabletop XFEL
Improving Maps and Models
Discussion Leader: Airlie McCoy (University of Cambridge, United Kingdom)
* Elspeth Garman (University of Oxford, United Kingdom) Unambig=
uous Metal Identification and Accurate Stoichiometric Measurements in Prote=
ins
* Frank Von Delft (Structural Genomics Consortium, United Kingd=
om) PANDDA: A Multi-Dataset Method for Electron Density Signal Extraction o=
f Superposed States such as Low-Occupancy Ligands
* James Fraser (University of California, San Francisco, USA) B=
irth of the Cool: Multitemperature X-Ray Crystallography to Reveal Protein =
Conformational Heterogeneity
* Paul Adams (Lawrence Berkeley Laboratory, USA) New Tools for =
Interpretation of Cryo-EM Maps
Tuesday 19th of July
Structural Biology Requires Multiple Methods
Discussion Leader: Nozomi Ando (Princeton University, USA)
* Allison Edwards (Bragg Institute, Australia) Neutron Diffract=
ion from Protein Crystals
* Neil Ranson (University of Leeds, United Kingdom) Experiences=
and Results Using the New Direct Electron Detectors for CryoEM
* Saikrishnan Kayarat (Indian Institute of Science Education an=
d Research, India) Mechanism of a Motor-Driven Endonuclease: Combining Stru=
ctural and Single-Molecule Approaches
* Nikolai Skrynnikov (Purdue University) Motions of Protein Mol=
ecules Within the Crystalline Lattice
* Sarah Bowman (MIT) What Can Spectroscopic Techniques Tell You=
About Your Crystal
Dynamically Resolved Methods
Discussion Leader: Carrie Wilmot (University of Minnesota, USA)
* Thomas Barends (Max-Planck Institute for Medical Research, Ge=
rmany) Ultrafast Functional Motions in Myoglobin Probed by Serial Femtoseco=
nd Crystallography
* Henrike Muller-Werkmeister (University of Toronto, Canada) Ti=
me-Resolved S(F)X Studies with a Fixed Target
* Gergely Katona (University of Gothenburg, Sweden) An Interlea=
ved Data Recording Method for Studying the Non-Thermal Effect of Terahertz =
Radiation on Protein Crystals
* Petra Fromme (Arizona State University, USA) Time-Resolved Fe=
mtosecond Crystallography: Towards Molecular Movies of Biomolecules 'In Act=
ion'
Wednesday 20th July
Hybridization of Synchrotron and XFEL Approaches
Discussion Leader: Aina Cohen (SSRL, USA)
* Elizabeth Baxter (SLAC National Accelerator Laboratory, USA) =
Alternative Methods for High Throughput Data Collection
* Manfred Burghammer (ESRF, France) Recent Developments in Seri=
al Micro-/Nano-Beam Diffraction X-Ray Techniques at ID13, ESRF
* Helen Ginn (University of Oxford, United Kingdom) Development=
of Methods in XFEL Analysis
* Thomas White (CFEL, Germany) Advances in Data Processing for =
Serial Femtosecond Crystallography
* Allen Orville (Diamond Light Source, UK) Dynamic Structural B=
iology: Awakened and Enabled by New Sources and Complementary Methods
Developments in Diffraction Methods
Discussion Leader: Nadia Zatsepin (Arizona State University)
* Isabel Uson (ICREA and the Spanish Research Council, Spain) A=
rcimboldo on Tour
* Kartik Ayyer (CFEL, Germany) Coherent Diffractive Imaging as =
a Structure Determination Tool for Disordered Crystals
* Andrea Thorne (MRC Laboratory of Molecular Biology, United Ki=
ngdom) Developments in Diffraction Data Analysis
Thursday 21st July
Selected Poster Presentations: New Cool Methods and Hot New Structures
Discussion Leader: James Fraser (University of California, San Francisco, U=
SA) Nine posters selected from the meeting for presentation.
Structural and Dynamical Information Beyond Bragg
Discussion Leader: James Holton (Advanced Light Source, USA)
* Michael Wall (Los Alamos National Laboratory, USA) Probing Pr=
otein Structural Dynamics Using Diffuse X-Ray Scattering
* Robert Rambo (Diamond Light Source Ltd, United Kingdom) A Rea=
l-Space Modelling Algorithm for SAXS Using Information Theory and Computati=
onal Geometry
* Nozomi Ando (Princeton University, USA) Untangling Protein Al=
lostery
Edward Snell Ph.D.
CEO Hauptman-Woodward Medical Research Institute
Assistant Prof. Department of Structural Biology, University at Buffalo
700 Ellicott Street, Buffalo, NY 14203-1102
Phone: (716) 898 8631 Fax: (716) 898 8660
Skype: eddie.snell Email: esnell at hwi.buffalo.edu
Heisenberg was probably here!
--_000_D59FD7F0451D6841823EB2778ADA485A03CCF76E94CAnewmandhcph_
Content-Type: text/html; charset="us-ascii"
Content-Transfer-Encoding: quoted-printable
<html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-micr=
osoft-com:office:office" xmlns:w=3D"urn:schemas-microsoft-com:office:word" =
xmlns:m=3D"http://schemas.microsoft.com/office/2004/12/omml" xmlns=3D"http:=
//www.w3.org/TR/REC-html40"><head><meta http-equiv=3DContent-Type content=
=3D"text/html; charset=3Dus-ascii"><meta name=3DGenerator content=3D"Micros=
oft Word 15 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:#0563C1;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:#954F72;
text-decoration:underline;}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri",sans-serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri",sans-serif;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext=3D"edit" spidmax=3D"1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext=3D"edit">
<o:idmap v:ext=3D"edit" data=3D"1" />
</o:shapelayout></xml><![endif]--></head><body lang=3DEN-US link=3D"#0563C1=
" vlink=3D"#954F72"><div class=3DWordSection1><p class=3DMsoNormal>Dear All=
,<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNor=
mal>This is not Phenix related but we do see a lot of representation from P=
henix developers and users at this conference. <o:p></o:p></p><p class=3DMs=
oNormal><o:p> </o:p></p><p class=3DMsoNormal>The 2016 Diffraction Meth=
ods in Structural Biology Gordon Research Conference (GRC) will be held at =
Bates College in Maine from July 17,to July 22nd 2016 - immediately before =
the American Crystallography Association Annual Meeting. The theme of this =
year’s conference is “Probing the Structure and Dynamics of Mac=
romolecules” and the conference celebrates its 40 year anniversary. &=
nbsp;Current details are available at <a href=3D"https://www.grc.org/progra=
ms.aspx?id=3D11655"><span style=3D'color:#0563C1'>https://www.grc.org/progr=
ams.aspx?id=3D11655</span></a>. Program details are below, it promises to b=
e an exciting. <o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p =
class=3DMsoNormal>Arwen Pearson (co-chair) and I would like to invite you t=
o consider attending the conference. Topics to be covered include new instr=
uments and opportunities on the horizon, methods to improve maps and models=
, complementary approaches, resolving dynamics, the interplay between XFEL =
and synchrotron, new diffraction developments, and structure beyond Bragg d=
iffraction. Many of the worlds experts in these areas will be at the meetin=
g and we encourage the participation of every level of expertise to cross-p=
ollinate the field. We will also have an opportunity for selected poster pr=
esenters to present talks at the meeting. <o:p></o:p></p><p class=3DM=
soNormal><o:p> </o:p></p><p class=3DMsoNormal>Applications for the con=
ference are now being accepted and will continue to be accepted until we ar=
e full.<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3D=
MsoNormal>From a personal perspective this is probably one of the best meet=
ings for those interested in the nuts and bolts of diffraction methods. It =
is also a unique opportunity to meet many of the key members of the field. =
It is a friendly and productive conference, and an exciting one in terms of=
getting a preview of the future. We encourage you to attend, take part in =
great science, and also interact in a less formal social and sometimes spor=
ting atmosphere.<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p=
class=3DMsoNormal>This will also be the second year that a related Gordon =
Research Seminar (GRS) is run. This is a meeting organized for and by post-=
docs and graduate students. Drs. Rike Mueller-Werkmeister and Bradely=
Hintze are organizing this with details at <a href=3D"https://www.grc.org/=
programs.aspx?id=3D16486"><span style=3D'color:#0563C1'>https://www.grc.org=
/programs.aspx?id=3D16486</span></a>. We strongly encourage laboratories wi=
th an interest in Diffraction Methods in Structural Biology to support thei=
r students in attending both the GRS and the GRC with the GRS serving as a =
useful introduction to the larger conference.<o:p></o:p></p><p class=3DMsoN=
ormal><o:p> </o:p></p><p class=3DMsoNormal>We are still raising funds =
for the GRS and GRC, in particular to enable younger scientists to attend. =
We are grateful and thank those who have supported us so far, and also thos=
e that are in the process of doing so. We are actively looking for further =
sponsorship.<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p cla=
ss=3DMsoNormal>Summer is a full time for meetings but this is going to be a=
very worthwhile one. Please pass this onto interested colleagues.<o:p></o:=
p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Thanks=
,<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNor=
mal>Eddie and Arwen<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p=
><p class=3DMsoNormal>Sunday 17th of July<o:p></o:p></p><p class=3DMsoNorma=
l><o:p> </o:p></p><p class=3DMsoNormal>Keynote Session: Structure and =
Dynamics<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader: Elspeth Garm=
an (University of Oxford, United Kingdom)<o:p></o:p></p><p class=3DMsoNorma=
l>• =
Carrie Wilmot (University of Minnesota, USA) MauG Catalysis: A Tale =
of Ferryl Heme, Radicals and Long-Distance Hopping<o:p></o:p></p><p class=
=3DMsoNormal>• &=
nbsp; Joseph Ferrara (Rigaku Americas Corporation, USA) A speci=
al talk to look back over 40 years of this GRC and describe the development=
s in the field since the first Diffraction Methods Meeting. <o:p></o:p></p>=
<p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Monday 18th =
July<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMso=
Normal>New Instruments and Opportunities<o:p></o:p></p><p class=3DMsoNormal=
>Discussion Leader: Sean McSweeny (NSLS-II, USA)<o:p></o:p></p><p class=3DM=
soNormal>•  =
; Armin Wagner (Diamond Light Source, United Kingdom) In-Vacuum=
Long-Wavelength Crystallography – First Results<o:p></o:p></p><p cla=
ss=3DMsoNormal>•  =
; Matthew Bowler (Synchrotron Crystallography Group, Fran=
ce) Fully Automatic Characterization and Data Collection: A New Tool for St=
ructural Biologist<o:p></o:p></p><p class=3DMsoNormal>• &n=
bsp; Marjolein Thunni=
ssen (MAX IV Laboratory, Sweden) Possibilities for Structural and Dynamical=
Studies on Proteins at MAX IV<o:p></o:p></p><p class=3DMsoNormal>•&n=
bsp; Esko=
Oskanen (European Spallation Source, Sweden) Structural Biology with Neutr=
ons – Opportunities at the European Spallation Source<o:p></o:p></p><=
p class=3DMsoNormal>• =
William Graves (Arizona State University) Electron=
Diffraction as a Method to Produce a Tabletop XFEL<o:p></o:p></p><p class=
=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Improving Maps and M=
odels<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader: Airlie McCoy (U=
niversity of Cambridge, United Kingdom) <o:p></o:p></p><p class=3DMsoNormal=
>• &=
nbsp; Elspeth Garman (University of Oxford, United Kingdom) Unambiguous Met=
al Identification and Accurate Stoichiometric Measurements in Proteins<o:p>=
</o:p></p><p class=3DMsoNormal>• &=
nbsp; Frank Von Delft (Structural Genomics Co=
nsortium, United Kingdom) PANDDA: A Multi-Dataset Method for Electron Densi=
ty Signal Extraction of Superposed States such as Low-Occupancy Ligands<o:p=
></o:p></p><p class=3DMsoNormal>• =
James Fraser (University of California=
, San Francisco, USA) Birth of the Cool: Multitemperature X-Ray Crystallogr=
aphy to Reveal Protein Conformational Heterogeneity<o:p></o:p></p><p class=
=3DMsoNormal>• &=
nbsp; Paul Adams (Lawrence Berkeley Laboratory, USA) New Tools =
for Interpretation of Cryo-EM Maps<o:p></o:p></p><p class=3DMsoNormal><o:p>=
</o:p></p><p class=3DMsoNormal>Tuesday 19th of July<o:p></o:p></p><p =
class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Structural Biol=
ogy Requires Multiple Methods<o:p></o:p></p><p class=3DMsoNormal>Discussion=
Leader: Nozomi Ando (Princeton University, USA) <o:p></o:p></p><p class=3D=
MsoNormal>• &nbs=
p; Allison Edwards (Bragg Institute, Australia) Neutron Diffrac=
tion from Protein Crystals<o:p></o:p></p><p class=3DMsoNormal>• =
Neil Ran=
son (University of Leeds, United Kingdom) Experiences and Results Using the=
New Direct Electron Detectors for CryoEM<o:p></o:p></p><p class=3DMsoNorma=
l>• =
Saikrishnan Kayarat (Indian Institute of Science Education and Resea=
rch, India) Mechanism of a Motor-Driven Endonuclease: Combining Structural =
and Single-Molecule Approaches<o:p></o:p></p><p class=3DMsoNormal>•&n=
bsp; Niko=
lai Skrynnikov (Purdue University) Motions of Protein Molecules Within the =
Crystalline Lattice<o:p></o:p></p><p class=3DMsoNormal>• &=
nbsp; Sarah Bowman (M=
IT) What Can Spectroscopic Techniques Tell You About Your Crystal<o:p></o:p=
></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Dynamic=
ally Resolved Methods<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader:=
Carrie Wilmot (University of Minnesota, USA)<o:p></o:p></p><p class=3DMsoN=
ormal>• &n=
bsp; Thomas Barends (Max-Planck Institute for Medical Research, Germa=
ny) Ultrafast Functional Motions in Myoglobin Probed by Serial Femtosecond =
Crystallography<o:p></o:p></p><p class=3DMsoNormal>•  =
; Henrike Muller-Werk=
meister (University of Toronto, Canada) Time-Resolved S(F)X Studies with a =
Fixed Target<o:p></o:p></p><p class=3DMsoNormal>• &n=
bsp; Gergely Katona (Univer=
sity of Gothenburg, Sweden) An Interleaved Data Recording Method for Studyi=
ng the Non-Thermal Effect of Terahertz Radiation on Protein Crystals<o:p></=
o:p></p><p class=3DMsoNormal>• &nb=
sp; Petra Fromme (Arizona State University, U=
SA) Time-Resolved Femtosecond Crystallography: Towards Molecular Movies of =
Biomolecules 'In Action'<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:=
p></p><p class=3DMsoNormal>Wednesday 20th July<o:p></o:p></p><p class=3DMso=
Normal><o:p> </o:p></p><p class=3DMsoNormal>Hybridization of Synchrotr=
on and XFEL Approaches<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader=
: Aina Cohen (SSRL, USA)<o:p></o:p></p><p class=3DMsoNormal>• &n=
bsp; Elizabeth =
Baxter (SLAC National Accelerator Laboratory, USA) Alternative Methods for =
High Throughput Data Collection<o:p></o:p></p><p class=3DMsoNormal>•&=
nbsp; Man=
fred Burghammer (ESRF, France) Recent Developments in Serial Micro-/Nano-Be=
am Diffraction X-Ray Techniques at ID13, ESRF<o:p></o:p></p><p class=3DMsoN=
ormal>• &n=
bsp; Helen Ginn (University of Oxford, United Kingdom) Development of=
Methods in XFEL Analysis<o:p></o:p></p><p class=3DMsoNormal>• &=
nbsp; Thomas Wh=
ite (CFEL, Germany) Advances in Data Processing for Serial Femtosecond Crys=
tallography<o:p></o:p></p><p class=3DMsoNormal>• &nb=
sp; Allen Orville (Diamond =
Light Source, UK) Dynamic Structural Biology: Awakened and Enabled by New S=
ources and Complementary Methods<o:p></o:p></p><p class=3DMsoNormal><o:p>&n=
bsp;</o:p></p><p class=3DMsoNormal>Developments in Diffraction Methods<o:p>=
</o:p></p><p class=3DMsoNormal>Discussion Leader: Nadia Zatsepin (Arizona S=
tate University)<o:p></o:p></p><p class=3DMsoNormal>• &nbs=
p; Isabel Uson (ICREA=
and the Spanish Research Council, Spain) Arcimboldo on Tour<o:p></o:p></p>=
<p class=3DMsoNormal>•  =
; Kartik Ayyer (CFEL, Germany) Coherent Diffractive=
Imaging as a Structure Determination Tool for Disordered Crystals<o:p></o:=
p></p><p class=3DMsoNormal>•  =
; Andrea Thorne (MRC Laboratory of Molecular =
Biology, United Kingdom) Developments in Diffraction Data Analysis<o:p></o:=
p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoNormal>Thursd=
ay 21st July<o:p></o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p cla=
ss=3DMsoNormal>Selected Poster Presentations: New Cool Methods and Hot New =
Structures<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader: James Fras=
er (University of California, San Francisco, USA) Nine posters selected fro=
m the meeting for presentation.<o:p></o:p></p><p class=3DMsoNormal><o:p>&nb=
sp;</o:p></p><p class=3DMsoNormal>Structural and Dynamical Information Beyo=
nd Bragg<o:p></o:p></p><p class=3DMsoNormal>Discussion Leader: James Holton=
(Advanced Light Source, USA)<o:p></o:p></p><p class=3DMsoNormal>•&nb=
sp; Micha=
el Wall (Los Alamos National Laboratory, USA) Probing Protein Structural Dy=
namics Using Diffuse X-Ray Scattering<o:p></o:p></p><p class=3DMsoNormal>&#=
8226; &nbs=
p; Robert Rambo (Diamond Light Source Ltd, United Kingdom) A Real-Space Mod=
elling Algorithm for SAXS Using Information Theory and Computational Geomet=
ry<o:p></o:p></p><p class=3DMsoNormal>• =
Nozomi Ando (Princeton Universit=
y, USA) Untangling Protein Allostery<o:p></o:p></p><p class=3DMsoNormal><o:=
p> </o:p></p><p class=3DMsoNormal><o:p> </o:p></p><p class=3DMsoN=
ormal><o:p> </o:p></p><p class=3DMsoNormal>Edward Snell Ph.D.<o:p></o:=
p></p><p class=3DMsoNormal>CEO Hauptman-Woodward Medical Research Institute=
<o:p></o:p></p><p class=3DMsoNormal>Assistant Prof. Department of Structura=
l Biology, University at Buffalo<o:p></o:p></p><p class=3DMsoNormal>700 Ell=
icott Street, Buffalo, NY 14203-1102<o:p></o:p></p><p class=3DMsoNormal>Pho=
ne: (716) 898 8631 &nb=
sp; Fax: (716) 898 8660 <o:p></o:p></p><p class=3DMsoNormal>Sky=
pe: eddie.snell =
Email: e=
snell at hwi.buffalo.edu <o:p></o:p></p><p class=3DMsoNormal><o:p> =
</o:p></p><p class=3DMsoNormal>Heisenberg was probably here!<o:p></o:p></p>=
<p class=3DMsoNormal><o:p> </o:p></p></div></body></html>=
--_000_D59FD7F0451D6841823EB2778ADA485A03CCF76E94CAnewmandhcph_--
More information about the phenixbb
mailing list