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<P DIR=LTR><SPAN LANG="en-us">I have a ligand with two phenyl rings where 2Fo and difference density clearly shows some torsion angle between the two rings. However, no matter how many times I tilt one ring refinement always makes them coplanar. Is there an option that I can use in phenix.refine to prevent the co-planarity or how do people typically handle this situation?</SPAN></P>
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<P DIR=LTR><SPAN LANG="en-us">Thanks for the help.</SPAN></P>
<P DIR=LTR><SPAN LANG="en-us">All the best,</SPAN></P>
<P DIR=LTR><SPAN LANG="en-us">-Jeff</SPAN></P>
<P DIR=LTR><SPAN LANG="en-us"></SPAN><SPAN LANG="en-us"></SPAN><A NAME=""><SPAN LANG="en-us">****************************************</SPAN></A></P>
<P DIR=LTR><SPAN LANG="en-us">Jeff Habel PhD</SPAN></P>
<P DIR=LTR><SPAN LANG="en-us">Scripps Florida</SPAN></P>
<P DIR=LTR><SPAN LANG="en-us">Drug Discovery</SPAN></P>
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<P DIR=LTR><SPAN LANG="en-us">Email: jhabel@scripps.edu</SPAN></P>
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