On Tue, Apr 6, 2010 at 1:30 PM, Pascal Egea <span dir="ltr"><<a href="mailto:pascal@msg.ucsf.edu">pascal@msg.ucsf.edu</a>></span> wrote:<br><div class="gmail_quote"><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex;">
<div>I wonder if there would be a simple way to get the Polygon program implemented in Phenix to use only membrane protein deposited structures as the reference data set. I understand that the reference set is much smaller than the whole menagerie of available structures but it represents an homogenous class of protein (crystallized in detergent).�</div>
<div>Do you think that this would be meaningful and useful?<br></div></blockquote><div><br></div><div>I think it is going to be limited by the relatively small sample size. �Membrane proteins are only about 1% of the PDB, and the comparison of statistics in Polygon really needs to be filtered by resolution - which isn't going to leave many structures to compare with, especially at high resolution.</div>
<div><br></div><div>-Nat</div></div>