<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><div><br></div><div><div>With apologies for duplicate postings:</div><div><br></div><div><br></div><div>The biannual Gordon Conference on Diffraction Methods in Structural Biology will be held at Bates College in Lewiston, Maine from 18-23rd July. The program covers all aspects of macromolecular structure solution from crystallization to structure solution and refinement and includes sessions on complementary techniques and the potential of free electron lasers. Many of the leading methods developers will be present and the format of the meeting, with free afternoons, provides ample opportunities for informal discussions.</div><div><br></div><div>Further details, including a full program and details on the application procedure can be obtained from:</div><div><br></div><div><a href="http://www.grc.org/programs.aspx?year=2010&program=diffrac">http://www.grc.org/programs.aspx?year=2010&program=diffrac</a></div><div><br></div><div>We hope to see you there !</div><div><br></div><div>Andrew Leslie (Chair) & Ana Gonzalez (Vice Chair)</div><div><br></div><div><br></div><div><font class="Apple-style-span" size="3"><span class="Apple-style-span" style="font-size: 12px; "><b>Outline Program:</b></span></font></div><div><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Sunday pm: Macromolecular Structures, Pushing the boundaries<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Michael Rossmann<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. ABC Transporters: Doug Rees</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>The Spliceosome : Kyoshi Nagai</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p><span class="Apple-style-span" style="font-weight: bold; ">Monday am:<span> </span>Crystallisation and the diffraction experiment</span></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Zbyszek Dauter<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Nanolitre crystallisation:<span> </span>Seth Harris</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>Twinning and disorder: Todd Yeates</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Simulating the diffraction experiment: James Holton</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. Microcrystallography:<span> </span>Gwyndaf Evans</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p><span class="Apple-style-span" style="font-weight: bold; ">Monday pm: Radiation damage and data collection strategies</span></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: </span><span lang="EN-US">Vivian Stojanoff<i></i></span><span lang="EN-US" style="color: black; "><o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Radiation damage, experimental: Elspeth Garman</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>Microbeams: Yanhui Zou</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Testing data collection strategies with the Pilatus: Marcus Mueller</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Tues am: Synchrotron developments and automated data processing<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Thomas Schneider<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Synchrotrons, latest developments: Sean Mc Sweeney</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Synchrotrons, latest developments:<span> </span>Janet Smith</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Data processing with Xia2/CHEF: Graeme Winter</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. Data processing with AUTOPROC: Clemens Vonrhein</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Tues pm:<span> </span>Complementary techniques<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Ana Gonzales<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Electron tomography: Sriram Subramaniam</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. SAXS: Hiro Tsuruta</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Spectroscopy: Carrie Wilmot</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Weds am: Structure solution and refinement<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader:<span> </span>Paul Adams<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. SAD Phasing: Randy Read</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Molecular replacement with BALBES: Garib Murshudov</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. PHENIX: Tom Terwilliger</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. TLS: Ethan Merritt</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Weds pm:<span> </span>Challenging problems/Membrane Proteins<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: TBC<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Using cubic lipidic phase: Martin Caffrey</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Membrane Proteins: Stephen White</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. The Bacterial Ribosome: Venki Ramakrishnan</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Thurs am:<span> </span>Selected Posters and Map improvement and Model building<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Tassos Perrakis<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. COOT: Paul Emsley</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Modelling nucleic acids: Johan Hattne</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Thursday pm: Future Methods, FELs, Diffraction imaging<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader:<span> </span>Ed Lattman<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1.<span> </span>Anton Barty</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">2. <span> </span>Serial Crystallography: John Spence and Petra Fromme<o:p></o:p></span></p><div><br></div></div></div></body></html>