<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><div><br></div><div>Just a reminder that there is still time to register for the Gordon Conference on Diffraction Methods in Structural Biology, that will be held at Bates College in Lewiston, Maine from 18-23rd July. </div><div><br></div><div>The program (see below) covers all aspects of macromolecular crystallography, from crystallization to structure solution and refinement, and includes sessions on complementary techniques and the potential of free electron lasers. </div><div><br></div><div>Many of the leading methods developers will be present and the format of the meeting, with free afternoons, provides ample opportunities for informal discussions.</div><div><br></div><div>Further details, including a full program and details on the application procedure can be obtained from:</div><div><br></div><div><a href="http://www.grc.org/programs.aspx?year=2010&program=diffrac">http://www.grc.org/programs.aspx?year=2010&program=diffrac</a></div><div><br></div><div>We hope to see you there !</div><div><br></div><div>Andrew Leslie (Chair) & Ana Gonzalez (Vice Chair)</div><div><br></div><div><br></div><div><font class="Apple-style-span" size="3"><span class="Apple-style-span" style="font-size: 12px; "><b>Outline Program:</b></span></font></div><div><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Sunday pm: Macromolecular Structures, Pushing the boundaries<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Michael Rossmann<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. ABC Transporters: Doug Rees</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>The Spliceosome : Kyoshi Nagai</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p><span class="Apple-style-span" style="font-weight: bold; ">Monday am:<span> </span>Crystallisation and the diffraction experiment</span></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Zbyszek Dauter<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Nanolitre crystallisation:<span> </span>Seth Harris</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>Twinning and disorder: Todd Yeates</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Simulating the diffraction experiment: James Holton</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. Microcrystallography:<span> </span>Gwyndaf Evans</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p><span class="Apple-style-span" style="font-weight: bold; ">Monday pm: Radiation damage and data collection strategies</span></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: </span><span lang="EN-US">Vivian Stojanoff<i></i></span><span lang="EN-US" style="color: black; "><o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Radiation damage, experimental: Elspeth Garman</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2.<span> </span>Microbeams: Yanhui Zou</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Testing data collection strategies with the Pilatus: Marcus Mueller</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Tues am: Synchrotron developments and automated data processing<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Thomas Schneider<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Synchrotrons, latest developments: Sean Mc Sweeney</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Synchrotrons, latest developments:<span> </span>Janet Smith</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Data processing with Xia2/CHEF: Graeme Winter</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. Data processing with AUTOPROC: Clemens Vonrhein</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Tues pm:<span> </span>Complementary techniques<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Ana Gonzales<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Electron tomography: Sriram Subramaniam</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. SAXS: Hiro Tsuruta</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. Spectroscopy: Carrie Wilmot</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Weds am: Structure solution and refinement<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader:<span> </span>Paul Adams<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. SAD Phasing: Randy Read</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Molecular replacement with BALBES: Garib Murshudov</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. PHENIX: Tom Terwilliger</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 4. TLS: Ethan Merritt</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Weds pm:<span> </span>Challenging problems/Membrane Proteins<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: TBC<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. Using cubic lipidic phase: Martin Caffrey</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Membrane Proteins: Stephen White</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 3. The Bacterial Ribosome: Venki Ramakrishnan</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Thurs am:<span> </span>Selected Posters and Map improvement and Model building<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader: Tassos Perrakis<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1. COOT: Paul Emsley</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 2. Modelling nucleic acids: Johan Hattne</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> </o:p></span></p><p class="MsoNormal"><b><span lang="EN-US" style="color: black; ">Thursday pm: Future Methods, FELs, Diffraction imaging<o:p></o:p></span></b></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">Discussion leader:<span> </span>Ed Lattman<o:p></o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; "><o:p> 1.<span> </span>Anton Barty</o:p></span></p><p class="MsoNormal"><span lang="EN-US" style="color: black; ">2. <span> </span>Serial Crystallography: John Spence and Petra Fromme<o:p></o:p></span></p><div><br></div></div></body></html>