<html><head><style type="text/css"><!-- DIV {margin:0px;} --></style></head><body><div style="font-family:arial,helvetica,sans-serif;font-size:10pt"><div>Hi,<br><br>I am new to phenix.refine. I'm using the graphical interface.<br>I hav processed my dfiffraction data and used Phaser MR for molecular replacement.<br>And I goyt a result: a solution pdb file and the associated mtz file.<br>1. So I use the mtz file from this Phaser MR solution or the original file from my data<br>processing in phenix.refine?<br>2. I have set parameters for phenix.refine like this:<br>Is there other settings for the parameter which I should do for a better result?<br>PDB data: my solution from Phaser MR<br>XRAY DATA= ????<br>Simulated Annealing=1000<br>Update waters<br>Refine Target weights: Wxc=0.8 Wxu=1.6<br>Cycles=5<br>Fix rotamers<br>Fix bad side chains<br></div>
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