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Hi Yuri,<br>
<br>
virtually any map computed using model phases is model biased.<br>
<br>
2mFo-DFc map computed with m and D estimated using "free"
reflections is less model biased than (Fobs, PHIcalc). See R.Read
(1986).<br>
<br>
Iterative-build OMIT maps seem to be the least model biased:<br>
<br>
<span class="Apple-style-span" style="color: rgb(0, 0, 0);
font-family: Verdana,Helvetica,Arial; font-size: 14px; font-style:
normal; font-variant: normal; font-weight: normal; letter-spacing:
normal; line-height: normal; orphans: 2; text-indent: 0px;
text-transform: none; white-space: normal; widows: 2;
word-spacing: 0px; background-color: rgb(238, 238, 232);"><b>Iterative-build
OMIT maps: map improvement by iterative model building and
refinement without model bias.</b><span
class="Apple-converted-space"> </span>T. C. Terwilliger, R. W.
Grosse-Kunstleve, P. V. Afonine, N. W. Moriarty, P. D. Adams, R.
J. Read, P. H. Zwart and L.-W. Hung<span
class="Apple-converted-space"> </span><a
href="http://www.iucr.org/cgi-bin/paper?wd5088"><i>Acta Cryst.</i><span
class="Apple-converted-space"> </span><b>D64</b>, 515-524
(2008)</a></span><br>
<br>
Pavel<br>
<br>
<br>
On 9/21/11 4:07 PM, Yuri wrote:
<blockquote cite="mid:3f7fd1731bf701e3b228cb49de3c58a0@ufl.edu"
type="cite">I was having a discussion with a friend about maps and
model bias.
<br>
Is the Fobs/PHImodel more biased than 2FOFCWT/PHI2FOFCWt?
<br>
What about an omit region of these two?
<br>
Thanks for any opinion on this
<br>
<br>
</blockquote>
<br>
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