<div dir="ltr">Got it, thank you!<div><br></div><div style>Mengbin</div></div><div class="gmail_extra"><br><br><div class="gmail_quote">On Wed, May 29, 2013 at 5:48 PM, Gino Cingolani <span dir="ltr">&lt;<a href="mailto:Gino.Cingolani@jefferson.edu" target="_blank">Gino.Cingolani@jefferson.edu</a>&gt;</span> wrote:<br>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">I would try to determine if there’s meaningful signal in your outer shell. You can try three things:</span></p>
<p><em><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;font-style:normal"><span>1.<span style="font:7.0pt &quot;Times New Roman&quot;">
</span></span></span></em><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Calculate a
<span>precision-indicating merging R factor (</span><em><span style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Rpim)</span></em><em><span style="font-family:&quot;Arial&quot;,&quot;sans-serif&quot;;font-style:normal"></span></em></span></p>

<p><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;"><span>2.<span style="font:7.0pt &quot;Times New Roman&quot;">
</span></span></span><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">(if you have ncs) calculate a self-rotation function using outer shell data only and see if you have meaningful information</span></p>

<p><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;"><span>3.<span style="font:7.0pt &quot;Times New Roman&quot;">
</span></span></span><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Scale less data together (although this may hurt your completeness depending on your space group).</span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;"> </span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;">Also try Scala instead of Scalepack.</span></p>
<p><span style="font-size:11.0pt;font-family:&quot;Arial&quot;,&quot;sans-serif&quot;"> </span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;;color:#1f497d"> </span></p>
<p class="MsoNormal" style="margin-bottom:12.0pt"><span style="font-size:11.0pt;font-family:&quot;Helvetica&quot;,&quot;sans-serif&quot;">******************************************************************************<br>

Gino Cingolani, Ph.D.<br>
Associate Professor<br>
Thomas Jefferson University<br>
Dept. of Biochemistry &amp; Molecular Biology<br>
233 South 10th Street - Room 826<br>
Office <a href="tel:%28215%29%20503%204573" value="+12155034573" target="_blank">(215) 503 4573</a><br>
Lab    <a href="tel:%28215%29%20503%204595" value="+12155034595" target="_blank">(215) 503 4595</a><br>
Fax    <a href="tel:%28215%29%20923%202117" value="+12159232117" target="_blank">(215) 923 2117</a><br>
E-mail:   <a href="mailto:gino.cingolani@jefferson.edu" target="_blank"><span style="color:blue">gino.cingolani@jefferson.edu</span></a><br>
Website:  <a href="http://www.cingolanilab.org/" target="_blank"><span style="color:blue">http://www.cingolanilab.org</span></a><br>
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&quot;Nati non foste per viver come bruti, ma per seguir virtute e canoscenza&quot;<br>
(&quot;You were not born to live like brutes, but to follow virtue and knowledge&quot;) Dante,
<br>
The Divine Comedy (Inferno,  XXVI, vv. 119-120)</span><span style="font-size:10.0pt;font-family:&quot;Tahoma&quot;,&quot;sans-serif&quot;"></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:&quot;Calibri&quot;,&quot;sans-serif&quot;;color:#1f497d"> </span></p>
<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:&quot;Tahoma&quot;,&quot;sans-serif&quot;">From:</span></b><span style="font-size:10.0pt;font-family:&quot;Tahoma&quot;,&quot;sans-serif&quot;"> <a href="mailto:phenixbb-bounces@phenix-online.org" target="_blank">phenixbb-bounces@phenix-online.org</a> [mailto:<a href="mailto:phenixbb-bounces@phenix-online.org" target="_blank">phenixbb-bounces@phenix-online.org</a>]
<b>On Behalf Of </b>Mengbin Chen<br>
<b>Sent:</b> Wednesday, May 29, 2013 5:37 PM<br>
<b>To:</b> PHENIX user mailing list<br>
<b>Subject:</b> [phenixbb] R-merge</span></p><div><div class="h5">
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<p class="MsoNormal">Dear Phenix Users,</p>
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<p class="MsoNormal">I have R-merge values equal 0.000 from highest resolution shell (which corresponds to values larger than 1.000) in a data set processed by HKL2000, with redundancies higher than 10 (I know this may help in increasing R-merge). I am not
sure if this is going to be a problem of Table 1 for the reviewers. Could you kindly drop me your suggestions?</p>
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<p class="MsoNormal">Mengbin Chen</p>
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<p class="MsoNormal">-- <br>
Mengbin Chen</p>
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<p class="MsoNormal">Department of Chemistry</p>
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<p class="MsoNormal">University of Pennsylvania</p>
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<br></blockquote></div><br><br clear="all"><div><br></div>-- <br>Mengbin Chen<div>Department of Chemistry</div><div>University of Pennsylvania</div>
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