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<div style="direction:ltr; font-family:Arial; color:#000000; font-size:12pt">Ed, <br>
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you are taking my words out of context. If you read my entire post ....:<br>
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"<b>I would try to determine if there’s meaningful signal in your outer shell</b>. You can try three things:<br>
1. Calculate a precision-indicating merging R factor (Rpim)2<br>
2. (if you have ncs) calculate a self-rotation function using outer shell data only and see if you have meaningful information<br>
3. <b>Scale less data together</b> (although this may hurt your completeness depending on space group)
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I'm not referring to cutting off data for refinement. I'm suggesting to analyze diffraction data before throwing them blindly in refinement,
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especially when the Rsym is that high. Scaling smaller batches of data is a simple way to detect problems such as radiation damages,
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change in unit cell parameters (quite common for large unit cell crystals), problems with detector, build up of ice, etc.
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******************************************************************************<br>
Gino Cingolani, Ph.D.<br>
Associate Professor<br>
Thomas Jefferson University<br>
Dept. of Biochemistry & Molecular Biology<br>
233 South 10th Street - Room 826<br>
Philadelphia PA 19107<br>
Office (215) 503 4573<br>
Lab (215) 503 4595<br>
Fax (215) 923 2117<br>
E-mail: gino.cingolani@jefferson.edu<br>
Website: http://www.cingolanilab.org<br>
******************************************************************************<br>
"Nati non foste per viver come bruti, ma per seguir virtute e canoscenza"<br>
("You were not born to live like brutes, but to follow virtue and knowledge") Dante,<br>
The Divine Comedy (Inferno, XXVI, vv. 119-120)<br>
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From: phenixbb-bounces@phenix-online.org [phenixbb-bounces@phenix-online.org] on behalf of Ed Pozharski [epozh001@umaryland.edu]<br>
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Sent: Wednesday, May 29, 2013 10:28 PM<br>
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To: PHENIX user mailing list<br>
<br>
Subject: Re: [phenixbb] R-merge<br>
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On 05/29/2013 05:48 PM, Gino Cingolani wrote:<br>
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Scale less data together<br>
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This seems a complete opposite of what an experimentalist should do (more data -> better, assuming no radiation damage). Can we give Rmerge proper burial at last?<br>
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-- <br>
Oh, suddenly throwing a giraffe into a volcano to make water is crazy?<br>
Julian, King of Lemurs<br>
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