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<p class="MsoNormal"><b><span lang="EN-US">Postdoctoral Position in Macromolecular Crystallography
</span></b></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">The Helmholtz Centre for Infection Research (HZI) in Braunschweig (Germany) announces an opening for a postdoctoral researcher in macromolecular crystallography. The position
is associated with the department “Structure and Function of Proteins” headed by Prof. Wulf Blankenfeldt. The department focuses on unraveling molecular mechanisms of uncharacterized processes in the metabolism, regulation and virulence of pathogenic microorganisms.
</span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal"><b><span lang="EN-US">About the institute</span></b></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">More than 800 people work at the HZI, a research institution in the Helmholtz Association of German Research Centres funded jointly by the Federal Republic of Germany and
the Federal State of Lower Saxony. The </span><span lang="EN-GB">centre’s</span><span lang="EN-US"> task is to undertake biomedical research in the field of infection biology to expand knowledge of the fundamental mechanisms behind medically relevant infectious
diseases with the aim of providing the key for the development of new therapeutics and vaccines.</span></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">The Department “Structure and Function of Proteins” offers excellent working conditions, state-of-the-art technical platforms and equipment (including bacterial, insect cell
and mammalian protein expression systems; access to a rotating anode X-ray source and several synchrotrons, crystal imaging and liquid handling systems; biophysical characterization of proteins), a lively scientific community and excellent support for the
development of personal soft-skills. </span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal" style="line-height:normal"><b><span lang="EN-US">Projects</span></b></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">All projects in our department aim at the identification and elucidation of the molecular function and mechanism of uncharacterized genes in pathogenic microorganisms. A
better understanding of these “white spaces” of the genome map will not only unravel interesting new molecular processes but also provide novel targets for pharmaceutical intervention. To achieve our goal, we employ a gamut of methods including – in addition
to structural biology – microbiological, biophysical and metabolomic techniques.
<b></b></span></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">Because our department is also the prime partner for structural biology-related questions at the HZI, the Technical University of Braunschweig and the German Centre for Infection
Research (</span><a href="http://www.dzif.de/en/"><span lang="EN-US">http://www.dzif.de/en/</span></a><span lang="EN-US">) the successful candidate will have the opportunity (and is expected) to take leading roles within our existing and emerging collaborations.
</span></p>
<p class="MsoNormal" style="line-height:normal"><b><span lang="EN-US"> </span></b></p>
<p class="MsoNormal" style="line-height:normal"><b><span lang="EN-US">Prerequisites</span></b></p>
<p class="MsoNormal" style="text-align:justify; line-height:normal"><span lang="EN-US">Candidates should hold a Ph.D. in a life sciences related subject at the time of their employment. They should have a strong background in all aspects of macromolecular crystallography,
including techniques of recombinant protein production and biophysical characterization. Experience in handling and manipulating pathogenic bacteria (biosafety level 2) is a plus.
<b></b></span></p>
<p class="MsoNormal" style="line-height:normal"><b><span lang="EN-US"> </span></b></p>
<p class="MsoNormal" style="line-height:normal"><b><span lang="EN-US">The handicapped</span></b></p>
<p class="MsoNormal" style="line-height:normal"><span lang="EN-US">Qualified applicants with a disability will be given preference.</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><b><span lang="EN-US" style="font-size:10.0pt; font-family:"Arial","sans-serif""> </span></b></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><b><span lang="EN-US" style="font-size:10.0pt; font-family:"Arial","sans-serif"">Job details</span></b></p>
<p class="MsoNormal"><span lang="EN-US">The position is available immediately for three years with a six month probation period. Salary is according to level E14 of the collective labor agreement for public service (TVöD).
</span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal"><b><span lang="EN-US">Application details</span></b></p>
<p class="MsoNormal"><span lang="EN-US">Candidates are asked to submit a full CV including a publication list, a cover letter outlining their interest in this position, a brief summary of current and past research experience (max. 2 pages) and contact data
of at least two referees. All documents and information should be provided in English or German.</span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span lang="EN-US" style="color:black">Applications should refer
<b>to code 05/2014 </b>and be sent by <b>28.02.2014 </b>to:</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span lang="EN-US" style="color:black"> </span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span lang="EN-US" style="color:black">Helmholtz Centre for Infection Research</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span lang="EN-US" style="color:black">Dept. of Human Resources</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span style="color:black">Inhoffenstraße 7</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span style="color:black">38124 Braunschweig</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span style="color:black">Germany</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span style="color:black">E-Mail:
</span><span style="color:blue">JobsHZI@helmholtz-hzi.de</span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span style="color:black"> </span></p>
<p class="MsoNormal" style="line-height:normal; text-autospace:none"><span lang="EN-US" style="color:black">For further information, please contact Prof. Dr. Wulf Blankenfeldt,</span></p>
<p class="MsoNormal"><span lang="EN-US" style="color:black">phone: +49-531-6181-7000, e-mail:
</span><span lang="EN-US" style="color:blue">wulf.blankenfeldt@helmholtz-hzi.de</span><span lang="EN-US"></span></p>
<p class="MsoNormal"><span lang="EN-US"> </span></p>
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Helmholtz-Zentrum für Infektionsforschung GmbH | Inhoffenstraße 7 | 38124 Braunschweig | www.helmholtz-hzi.de<br>
Das HZI ist seit 2007 zertifiziertes Mitglied im "<b>audit</b> beruf<b>und</b>familie"<br>
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Vorsitzende des Aufsichtsrates: MinDir’in Bärbel Brumme-Bothe, Bundesministerium für Bildung und Forschung<br>
Stellvertreter: MinDirig Rüdiger Eichel, Niedersächsisches Ministerium für Wissenschaft und Kultur<br>
Geschäftsführung: Prof. Dr. Dirk Heinz; Franziska Broer<br>
Gesellschaft mit beschränkter Haftung (GmbH)<br>
Sitz der Gesellschaft: Braunschweig<br>
Handelsregister: Amtsgericht Braunschweig, HRB 477<br>
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