<div dir="ltr">Thanks, Nat. <div><br></div><div>If this is noise, why the anomalous or LLG peaks could be as high as 5 ~ 6 sigma? </div><div><br></div><div>Charles</div></div><div class="gmail_extra"><br><div class="gmail_quote">On Tue, Sep 9, 2014 at 5:58 PM, Nathaniel Echols <span dir="ltr"><<a href="mailto:nechols@lbl.gov" target="_blank">nechols@lbl.gov</a>></span> wrote:<br><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><span class="">On Tue, Sep 9, 2014 at 8:40 AM, CPMAS Chen <span dir="ltr"><<a href="mailto:cpmasmit@gmail.com" target="_blank">cpmasmit@gmail.com</a>></span> wrote:<br></span><div class="gmail_extra"><div class="gmail_quote"><span class=""><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex"><div dir="ltr"><div>Is it possible that I have anomalous and LLG peak, but I have no difference density peak? In this case, is that because the model I have is not good enough or the diffraction data at this site of the model is missing?</div></div></blockquote><div><br></div></span><div>You should at a minimum see > 1sigma density in the 2mFo-DFc map, and if the site is unmodeled (or modeled as a water) you should see an mFo-DFc peak as well. If neither of these applies, the anomalous and LLG peaks are probably just noise.</div><div><br></div><div>-Nat </div></div></div></div>
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<p></p><p>***************************************************</p><p>Charles Chen</p><p>Research Associate</p><p>University of Pittsburgh School of Medicine</p><p>Department of Anesthesiology</p><p>******************************************************</p><p></p>
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