<div dir="ltr">On Fri, Nov 14, 2014 at 2:06 PM, Dale Tronrud <span dir="ltr"><<a href="mailto:detBB@daletronrud.com" target="_blank">detBB@daletronrud.com</a>></span> wrote:<br><div class="gmail_extra"><div class="gmail_quote"><blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">
You also asked if burning your crystals could improve the map. If<br>
you have more crystals I would recommend soaking them in a higher<br>
concentration of ligand. No amount of fancy data collection is going<br>
to make the density of a low occupancy compound stronger. Getting the<br>
occupancy up will do you worlds of good.</blockquote><div><br></div><div>But won't measuring the weak high-resolution reflections as accurately as possible help resolve map details like partial-occupancy atoms? (Although I think it's better to do this by collecting more redundant data than increasing the exposure time.)</div><div><br></div><div>-Nat</div></div></div></div>