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    Why you want to decrease B-factor?<br>
    Pavel<br>
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    <div class="moz-cite-prefix">On 7/25/15 07:40, Smith Liu wrote:<br>
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        <div>Suppose a 500-aa protein crystal structure has a flexible
          loop of 30 aas, and the loop fragment has a relatively high
          b-factor (above 100) in comparison with the whole protein
          b-factor. Is any refine strategy we can refine so that the
          b-factor of that loop fragment will be decreased?<br>
          <br>
          Smith<br>
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