<html><body><div style="color:#000; background-color:#fff; font-family:HelveticaNeue, Helvetica Neue, Helvetica, Arial, Lucida Grande, sans-serif;font-size:16px"><div id="yui_3_16_0_1_1444096510181_11622"> Dear All,</div><div id="yui_3_16_0_1_1444096510181_11623"><br></div><div id="yui_3_16_0_1_1444096510181_11624">For the phenix refine of a protein-ligand complex, is the ligand cif file a necessity? If we do not add the cif file, what will occur?</div><div id="yui_3_16_0_1_1444096510181_11680"><br></div><div id="yui_3_16_0_1_1444096510181_11679">Best regards.</div><div id="yui_3_16_0_1_1444096510181_11688"><br></div><div>Smith</div></div></body></html>