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P.S.: <br>
<br>
<div class="moz-cite-prefix">If atom is misplaced normally you would
see both: positive and negative residual density in close
proximity to each other. <br>
<br>
If you only see negative density at SG centers this may mean the
site is partially occupied.<br>
<br>
Pavel<br>
<br>
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cite="mid:368539498.3207258.1455485080089.JavaMail.yahoo@mail.yahoo.com"
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<div id="yui_3_16_0_1_1455483927872_4897" dir="ltr">Sorry, my
previous email was incomplete. My structure has negative
density in the center of some disulfides (the magnitude of
this effect vary between different monomers in the ASU). I'd
like to refine the structure in an "artificial reduced form",
where cysteines involved in disulfides are treated in reduced
form, but repulsions originating from neighboring sulfur atoms
are turned-off, to monitor distances (I expect that SG atoms
remain close to 2 A), guided only by data. Thank you,<br>
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<br>
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