<html><head></head><body><div style="color:#000; background-color:#fff; font-family:HelveticaNeue, Helvetica Neue, Helvetica, Arial, Lucida Grande, Sans-Serif;font-size:16px"><div id="yui_3_16_0_1_1456607631682_6139">Hi,</div><div dir="ltr" id="yui_3_16_0_1_1456607631682_6138">I have a confusion regarding solving iodine SAD-data in Phaser-EP.</div><div id="yui_3_16_0_1_1456607631682_6575" dir="ltr">1. GUI result shows Log-likelihood gain: 115037.70 and FOM: 0.527. But in log file</div><div id="yui_3_16_0_1_1456607631682_6326" dir="ltr"><br></div><div id="yui_3_16_0_1_1456607631682_6327" dir="ltr"> SAD Refinement Table (Sorted)<br> -----------------------------<br> SET SpaceGroup FOM Log-Likelihood Rfac Composition I <br> # 1 P 21 21 2 0.53 -115038 69.4 23 </div><div id="yui_3_16_0_1_1456607631682_6342" dir="ltr"><br></div><div id="yui_3_16_0_1_1456607631682_6368" dir="ltr">Why there is negative value of Log-Likelihood in log file? Is Log-Likelihood and Log-likelihood gain is two different things?</div><div id="yui_3_16_0_1_1456607631682_6493" dir="ltr">Has Phaser solved it? <br></div><div id="yui_3_16_0_1_1456607631682_6502" dir="ltr">When I feed these results to Autobuild, the model was ~80 % complete with Rfree and Rwork of 0.3171 and 0.2754 and Model Map correlation 0.74. Model was further refined in phenix.refine upto Rfree = 0.27.</div><div id="yui_3_16_0_1_1456607631682_6517" dir="ltr"><br></div><div id="yui_3_16_0_1_1456607631682_6525" dir="ltr">2. When I am solving same dataset with Autosol and Autobuild, the dimer orientation have changed? Is this 'normal' or one of the solution is wrong and if it then which one should choose to refine further?</div><div id="yui_3_16_0_1_1456607631682_6591" dir="ltr"><br></div><div id="yui_3_16_0_1_1456607631682_6604" dir="ltr">Thanks in advance.<br></div></div></body></html>