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    Hi Jack,<br>
    <br>
    Polygon tool is designed answer questions like "what Rwork, Rfree
    and Rfree-Rwork I expect at this resolution?". <br>
    If focusing on R-factors only, then you can get a quick idea using a
    command line tool:<br>
    <br>
    <tt>phenix.r_factor_statistics 2.25</tt><tt><br>
    </tt><tt><br>
    </tt><tt>Histogram of Rwork for models in PDB at resolution
      2.15-2.35 A:</tt><tt><br>
    </tt><tt>���� 0.123 - 0.144����� : 36</tt><tt><br>
    </tt><tt>���� 0.144 - 0.165����� : 442</tt><tt><br>
    </tt><tt>���� 0.165 - 0.187����� : 1669</tt><tt><br>
    </tt><tt>���� 0.187 - 0.208����� : 2782</tt><tt><br>
    </tt><tt>���� <b>0.208 - 0.230����� : 2023</b></tt><b><tt>
        &lt;&lt;&lt; Your case<br>
      </tt></b><b><tt>���� 0.230 - 0.251����� : 812</tt></b><tt><br>
    </tt><tt>���� 0.251 - 0.273����� : 165</tt><tt><br>
    </tt><tt>���� 0.273 - 0.294����� : 19</tt><tt><br>
    </tt><tt>���� 0.294 - 0.316����� : 5</tt><tt><br>
    </tt><tt>���� 0.316 - 0.337����� : 3</tt><tt><br>
    </tt><tt>Histogram of Rfree for models in PDB at resolution
      2.15-2.35 A:</tt><tt><br>
    </tt><tt>���� 0.160 - 0.183����� : 43</tt><tt><br>
    </tt><tt>���� 0.183 - 0.207����� : 405</tt><tt><br>
    </tt><tt>���� 0.207 - 0.231����� : 1485</tt><tt><br>
    </tt><tt>���� 0.231 - 0.255����� : 2759</tt><tt><br>
    </tt><b><tt>���� 0.255 - 0.278����� : 2216</tt></b><tt><b>
        &lt;&lt;&lt; Your case</b><br>
    </tt><tt>���� 0.278 - 0.302����� : 861</tt><tt><br>
    </tt><tt>���� 0.302 - 0.326����� : 142</tt><tt><br>
    </tt><tt>���� 0.326 - 0.350����� : 36</tt><tt><br>
    </tt><tt>���� 0.350 - 0.373����� : 7</tt><tt><br>
    </tt><tt>���� 0.373 - 0.397����� : 2</tt><tt><br>
    </tt><tt>Histogram of Rfree-Rwork for all model in PDB at resolution
      2.15-2.35 A:</tt><tt><br>
    </tt><tt>���� 0.001 - 0.011����� : 55</tt><tt><br>
    </tt><tt>���� 0.011 - 0.021����� : 247</tt><tt><br>
    </tt><tt>���� 0.021 - 0.031����� : 782</tt><tt><br>
    </tt><tt>���� 0.031 - 0.041����� : 1597</tt><tt><br>
    </tt><b><tt>���� 0.041 - 0.050����� : 2124</tt></b><tt><b>
        &lt;&lt;&lt; Your case</b><br>
    </tt><tt>���� 0.050 - 0.060����� : 1716</tt><tt><br>
    </tt><tt>���� 0.060 - 0.070����� : 912</tt><tt><br>
    </tt><tt>���� 0.070 - 0.080����� : 316</tt><tt><br>
    </tt><tt>���� 0.080 - 0.090����� : 131</tt><tt><br>
    </tt><tt>���� 0.090 - 0.100����� : 76</tt><tt><br>
    </tt><tt>Number of structures considered: 7956</tt><br>
    <br>
    So it looks like R-factors you have is what one would expect at this
    resolution.<br>
    <br>
    Pavel<br>
    <br>
    <div class="moz-cite-prefix">On 4/12/18 18:38, Tanner, John J.
      wrote:<br>
    </div>
    <blockquote type="cite"
      cite="mid:1CBEEA6C-F632-4D04-9BAB-7E7F91528DFE@missouri.edu">
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      Dear PhenixBB,
      <div class=""><br class="">
      </div>
      <div class="">We have a crystal form that xtriage flags as having
        strong translational pseudo symmetry (Patterson peak 57% the
        height of the origin peak, p-value = 3E-5).�
        <div class=""><br class="">
        </div>
        <div class="">The space group is P21212. We can solve the
          structure with MR and refine to R=0.233 and R-free =0.276 at
          2.25 Angstrom resolution. The maps look very good, but do not
          suggest major additional modeling that could be done to
          improve the structure and lower the R-factors. I know that one
          expects the R-factors from refinement to be higher when TPS is
          present, but my question is how high is too high? �Has anyone
          done a study that shows the expectations for R-factors when
          TPS is present?�</div>
        <div class=""><br class="">
        </div>
        <div class="">Thanks,</div>
        <div class=""><br class="">
        </div>
        <div class="">Jack�</div>
        <div class=""><br class="">
          <div class="">
            <div class="">
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                          class="">
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                            after-white-space;" class="">
                            <div style="orphans: 2; text-align:
                              -webkit-auto; text-indent: 0px; widows: 2;
                              word-wrap: break-word; -webkit-nbsp-mode:
                              space; -webkit-line-break:
                              after-white-space;" class="">
                              <div style="color: rgb(0, 0, 0);
                                font-family: Helvetica; font-style:
                                normal; font-variant-ligatures: normal;
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                                font-variant-position: normal;
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                                normal; line-height: normal;
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                                class="">
                                John J. Tanner<br class="">
                                Interim Chair, Department of
                                Biochemistry�</div>
                              <div style="color: rgb(0, 0, 0);
                                font-family: Helvetica; font-style:
                                normal; font-variant-ligatures: normal;
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                                font-variant-position: normal;
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                                normal; line-height: normal;
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                                normal; word-spacing: 0px;
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                                class="">
                                Professor of�Biochemistry�and�Chemistry</div>
                              <div style="color: rgb(0, 0, 0);
                                font-family: Helvetica; font-style:
                                normal; font-variant-ligatures: normal;
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                                font-variant-position: normal;
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                                text-transform: none; white-space:
                                normal; word-spacing: 0px;
                                -webkit-text-stroke-width: 0px;"
                                class="">
                                <span style="text-align: -webkit-auto;"
                                  class="">Department of Biochemistry</span></div>
                              <div style="color: rgb(0, 0, 0);
                                font-family: Helvetica; font-style:
                                normal; font-variant-ligatures: normal;
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                                class="">
                                University of Missouri-Columbia<br
                                  class="">
                                117 Schweitzer Hall</div>
                              <div class="">503 S College Avenue<br
                                  class="">
                                Columbia, MO 65211<br class="">
                                Phone: 573-884-1280</div>
                              <div style="color: rgb(0, 0, 0);
                                font-family: Helvetica; font-style:
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                                -webkit-text-stroke-width: 0px;"
                                class="">
                                Fax:�573-882-5635<br class="">
                                Email:�<a
                                  href="mailto:tannerjj@missouri.edu"
                                  class="" moz-do-not-send="true">tannerjj@missouri.edu</a><br
                                  class="">
                                <a
                                  href="http://faculty.missouri.edu/%7Etannerjj/tannergroup/tanner.html"
                                  class="" moz-do-not-send="true">http://faculty.missouri.edu/~tannerjj/tannergroup/tanner.html</a></div>
                              <div style="color: rgb(0, 0, 0);
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                                normal; word-spacing: 0px;
                                -webkit-text-stroke-width: 0px;"
                                class="">
                                Lab: Schlundt Annex rooms 3,6,9, 203B,
                                203C</div>
                              <div style="color: rgb(0, 0, 0);
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                                class="">
                                Office:�Schlundt Annex 203A</div>
                            </div>
                          </div>
                        </div>
                      </div>
                    </div>
                  </div>
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