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<div class="">System:<span class="Apple-tab-span" style="white-space: pre;"> </span>
macOS 10.13.6</div>
<div class="">Phenix version:<span class="Apple-tab-span" style="white-space: pre;">
</span>phenix-1.14rc1-3177</div>
<div class="">Rosetta version:<span class="Apple-tab-span" style="white-space: pre;">
</span>3.9 (rosetta_src_2018.09.60072_bundle)</div>
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<div class="">So I rebuilt rosetta 3.9 as root and can now run &quot;Rosetta refinement&quot;. However...Rosetta refinement ran for 2 hours, slowly gobbling memory up to a maximum of 25GB before failing (error below).</div>
<div class="">Also gobbled up disk space, creating a 78 GB file “outtmp.map”.</div>
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<div class="">A memory leak issue?</div>
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<div class="">Thanks,</div>
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<div class="">a&#43;&#43;</div>
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RuntimeError : File 'None' not found.</div>
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Traceback:</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/cctbx_project/libtbx/runtime_utils.py&quot;, line 179, in run</div>
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&nbsp; &nbsp; return_value = self.target()</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/cctbx_project/libtbx/runtime_utils.py&quot;, line 74, in __call__</div>
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&nbsp; &nbsp; result = self.run()</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/phenix/phenix/command_line/rosetta_refine.py&quot;, line 304, in run</div>
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&nbsp; &nbsp; return run(args=list(self.args))</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/phenix/phenix/command_line/rosetta_refine.py&quot;, line 191, in run</div>
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&nbsp; &nbsp; debug=params.output.debug)</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/phenix/phenix/rosetta/refine.py&quot;, line 313, in __init__</div>
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&nbsp; &nbsp; self.run_jobs()</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/phenix/phenix/rosetta/refine.py&quot;, line 388, in run_jobs</div>
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&nbsp; &nbsp; check_result(result)</div>
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&nbsp; File &quot;/Applications/phenix-1.14rc1-3177/modules/phenix/phenix/rosetta/refine.py&quot;, line 383, in check_result</div>
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&nbsp; &nbsp; raise RuntimeError(&quot;File '%s' not found.&quot; % result.file_name)</div>
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