<div dir="ltr"><div dir="ltr"><div class="gmail_default" style="font-family:trebuchet ms,sans-serif;font-size:small">Hello All,<br><br>I am solving a X-ray crystal structure of protein-DNA 
complex at 2.3 Angs. In my structure, it seems like the the duplex DNA 
is bound in two different conformations, and both the conformations are 
occupied in same density. I wish to know how to refine the alternative 
conformations of the DNA duplex in Phenix. In am using Phenix GUI. <br><br>Thanks<br>Abhishek</div><div><div dir="ltr" class="gmail_signature"><div dir="ltr"><div><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div dir="ltr"><div><p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><b><span style="font-size:12pt;font-family:&quot;Courier New&quot;;color:rgb(0,77,187)"><span class="gmail_default" style="font-family:trebuchet ms,sans-serif;font-size:small">______________________________________________</span><br></span></b></p><p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><b><span style="font-size:12pt;font-family:&quot;Courier New&quot;;color:rgb(0,77,187)">Abhishek Suman</span></b><span style="font-family:&quot;Courier New&quot;"><span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><i><span style="font-family:&quot;Courier New&quot;;color:rgb(0,77,187)">Research Scholar, PhD</span></i><span style="font-family:&quot;Courier New&quot;"><span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">C/o,
Dr. Rajakumara Eerappa<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Macromolecular
Structural Biology Group<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Department
of Biotechnology<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">R#
517,315, Academic Block - A<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Indian
Institute of Technology Hyderabad<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Kandi
502 285 Sangareddy<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Telangana
INDIA<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Contact: +91 91002 74548 (O)<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">         +91 80843 11898 (R)<span></span></span></p>

<p class="MsoNormal" style="margin-bottom:0.0001pt;line-height:normal"><span style="font-family:&quot;Courier New&quot;">Email: <a href="mailto:abhisheks.iith@gmail.com" target="_blank">abhisheks.iith@gmail.com</a></span></p><div><span style="font-family:Verdana,sans-serif;font-size:9.5pt">-----------------------------------------------------------------</span><br></div><p style="font-size:12.8px;margin:0in 0in 0.0001pt;background-image:initial;background-position:initial;background-repeat:initial">













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