<html><head><meta http-equiv="Content-Type" content="text/html; charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><font face="ArialMT" size="2" class="">Dear Colleagues,</font><div class=""><font face="ArialMT" size="2" class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><b class="">POSITION: </b> </font><font face="ArialMT" size="2" class="">Synchrotron Macromolecular Crystallographer</font></div><div class=""><font face="ArialMT" size="2" class=""><b class="">LOCATION:</b> IMCA-CAT at the Advanced Photon Source (near Chicago, IL)</font></div><div class=""><p class="MsoNormal" style="margin-top: 6pt;"><font face="ArialMT" size="2" class=""><br class=""></font></p><p class="MsoNormal" style="margin-top: 6pt;"><font face="ArialMT" size="2" class="">The Industrial Macromolecular Crystallography Association - Collaborative Access Team (IMCA-CAT) and the Hauptman-Woodward Medical Research Institute (HWI) seek an inventive macromolecular crystallographer to join the IMCA-CAT team in accelerating pharmaceutical drug discovery through synchrotron-based structural biology research. As an employee of HWI, you will be based at the center of the team’s operations at the Advanced Photon Source (APS), Argonne National Laboratory, near Chicago, IL. This is an ideal position for a motivated scientist who is passionate about delivering strategic value, developing new technologies, and working in a high- powered, collaborative environment.</font></p><font face="ArialMT" size="2" class=""><br class=""><b class="">DESCRIPTION:</b><br class="">This is an exciting time to join IMCA-CAT. Underway this summer is the first of a two-phase upgrade that will significantly increase throughput and establish a strong foundation upon which to build capacity. The second phase upgrade, currently in design, will profoundly increase capacity and dramatically expand capability for challenging research projects.<br class=""><br class="">The successful candidate will be an integral part of these upgrade activities while maintaining flow of diffraction data for pharmaceutical research projects. The candidate will work closely with IMCA-CAT colleagues in an inclusive and respectful environment, and is expected to take initiative and contribute to the team effort.<br class=""><br class="">On any given day, you will do one or all of these things:<br class=""></font><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Contribute to drug discovery research efforts using a growing portfolio of synchrotron sources.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Enhance the structural biology programs for pharmaceutical structure-based drug design.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Provide experiment support for scientists from the structural biology community who conduct research using the IMCA-CAT synchrotron beamlines.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Ensure beamline instrumentation is operational and produces data of the highest quality.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Expand the experiment envelope of the beamline.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Establish efficient protocols for accelerating data acquisition while enhancing data security.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Develop automated methods for acquiring quality data from challenging samples.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Participate in highly collaborative working groups.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Engage in the technical development of new strategies for ultra-high throughput.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Collaborate with staff on strategically-aligned research and development projects.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Communicate with researchers and present at meetings.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Conduct independent and/or collaborative research.<br class=""><br class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><b class="">DESIRED SKILLS and EXPERIENCE:</b><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• PhD in a relevant field.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Expertise in macromolecular crystallography.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Outstanding experimental skills.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Considerable mechanical skills.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Highly collaborative and team-oriented approach to conducting work and solving problems.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Excellent written and oral communication skills.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Deeply proactive approach to meeting and exceeding goals.<br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><span class="Apple-tab-span" style="white-space: pre;"> </span>• Ability to meet requirements for site access to Argonne National Laboratory.<br class=""><br class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><b class="">TO APPLY:</b><br class="">Send an introductory email, cv, and contact information for three references to Lisa Keefe, IMCA-CAT Director and HWI Vice President of Advancing Therapeutics, at <a href="mailto:keefe@imca-cat.org" class="">keefe@imca-cat.org</a>.<br class=""><br class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><b class="">LEARN MORE:</b><br class="">Visit our websites to learn more about IMCA-CAT (<a href="http://www.imca-cat.org" class="">www.imca-cat.org</a>) and HWI (<a href="http://www.hwi.buffalo.edu" class="">www.hwi.buffalo.edu</a>). </font></div><div class=""><font face="ArialMT" size="2" class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class=""><br class=""></font></div><div class=""><font face="ArialMT" size="2" class="">HWI is an equal opportunity employer.</font></div><div class=""><div class=""><span style="line-height: normal; orphans: 2; widows: 2;" class=""><div style="font-variant-ligatures: normal; font-variant-position: normal; font-variant-numeric: normal; font-variant-alternates: normal; font-variant-east-asian: normal;" class=""><div style="line-height: normal; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><br class=""></div></div></div></span></div></div></div><div class="">
<div style="color: rgb(0, 0, 0); font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px;" class=""><span style="line-height: normal; orphans: 2; widows: 2;" class=""><div style="font-variant-ligatures: normal; font-variant-position: normal; font-variant-numeric: normal; font-variant-alternates: normal; font-variant-east-asian: normal;" class=""><div style="line-height: normal; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><div style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class=""><br class="Apple-interchange-newline"><hr size="1" width="100%" noshade="" align="center" class="" style="color: rgb(31, 73, 125); font-family: Calibri, sans-serif; text-align: center;"><div class=""><b style="line-height: normal; orphans: 2; widows: 2;" class=""><font size="1" class=""><font face="Verdana, Helvetica, Arial" class=""><span style="font-size: 9pt;" class="">Lisa J Keefe, PhD</span></font></font></b></div></div></div></div></span></div><font style="font-variant-caps: normal; letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; line-height: normal; orphans: 2; widows: 2;" class=""><span style="font-variant-caps: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;"><span><br class="Apple-interchange-newline" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; font-size: 14px;"><span style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; font-size: 14px;"><span><span><span><span><span><span><span><span><span><span><span><span><span><span style="color: rgb(0, 0, 0);"><span style="font-family: Helvetica; font-size: 14px; font-weight: normal; font-style: normal;"><span><span><span><span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></span></font></div></body></html>