<html>
<head>
<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252">
<style type="text/css" style="display:none;"> P {margin-top:0;margin-bottom:0;} </style>
</head>
<body dir="ltr">
<div style="font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<div style="margin: 0px; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt">
<p style="margin: 3pt 0in 12pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">Postdoctoral position open at the University of Massachusetts Medical School, in the Korostelev Lab:<span style="margin: 0px"> </span></span><span style="margin: 0px"><u><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px; color: blue">https://www.umassmed.edu/korostelev-lab/</span></u></span><u><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px; color: blue">.</span></u><span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"></span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome's central role in bacterial
stress<span style="margin: 0px"> </span>signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some lab publications are provided below.</span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"> </span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community:<span style="margin: 0px"> </span></span><span style="margin: 0px"><u><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px; color: blue">https://www.umassmed.edu/rti/about-the-rti/faculty-members/</span></u></span><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">.
Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development.</span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px"><br>
We seek a highly motivated person who very recently received a PhD, or will soon receive a PhD.<span style="margin: 0px"> <span style="margin: 0px"> </span></span>Applications sent prior to the dissertation defense date are welcome.<br>
<br>
Please submit the following information via email to:<span style="margin: 0px"> </span></span><i><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">ann.powers@umassmed.edu</span></i><i><span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px"></span></i></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">1)<span style="margin: 0px"> <span style="margin: 0px"> </span></span>your CV (including publication list);<br>
2)<span style="margin: 0px"> <span style="margin: 0px"> </span></span>in less than 2 pages, an outline of your:<span style="margin: 0px"> </span></span><span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"></span></p>
<p style="margin: 3pt 0in 0.0001pt 0.5in; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px"> (i) previous work - focusing on your most interesting finding(s);<span style="margin: 0px"> </span></span><span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"></span></p>
<p style="margin: 3pt 0in 0.0001pt 0.5in; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px"> (ii) your current/future scientific interests, and whether/which aspects of translation regulation sound interesting to you;</span><span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"></span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt; line-height: 19.200000762939453px">3)<span style="margin: 0px"> </span><span style="margin: 0px"> <span style="margin: 0px"> </span></span>email addresses of three references.</span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: 17.600000381469727px; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-size: 12pt; line-height: 19.200000762939453px"> </span></p>
<p style="margin: 3pt 0in 0.0001pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">Selected publications (accessible via the provided links):</span><span style="margin: 0px; font-size: 12pt"></span></p>
<p style="margin: 6pt 0in 0.0001pt 23.75pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"; text-indent: -0.2in">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">-</span><span style="margin: 0px; font-size: 7pt"> </span><span style="margin: 0px; font-family: Arial; font-size: 12pt">Svidritskiy et al. �</span><a href="https://elifesciences.org/articles/46850" target="_blank" rel="noopener noreferrer" style="margin: 0px; color: purple; text-decoration: underline"><span style="margin: 0px; font-family: Arial; font-size: 12pt">Extensive
ribosome and RF2 rearrangements during translation termination</span></a><span style="margin: 0px; font-family: Arial; font-size: 12pt">�.<span style="margin: 0px"> </span><i>eLife.</i>2019.</span><span style="margin: 0px; font-size: 12pt"></span></p>
<p style="margin: 6pt 0in 0.0001pt 23.75pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"; text-indent: -0.2in">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">-</span><span style="margin: 0px; font-size: 7pt"> </span><span style="margin: 0px; font-family: Arial; font-size: 12pt">Loveland et al. �</span><span style="margin: 0px; font-family: Arial; font-size: 12pt"><a href="https://www.nature.com/articles/nature22397" target="_blank" rel="noopener noreferrer" title="https://www.nature.com/articles/nature22397" style="margin: 0px">Ensemble
cryo-EM elucidates the mechanism of translation fidelity</a></span><span style="margin: 0px; font-family: Arial; font-size: 12pt">�.<span style="margin: 0px"> </span><i>Nature</i>. 2017.</span><span style="margin: 0px; font-size: 12pt"></span></p>
<p style="margin: 6pt 0in 0.0001pt 23.75pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"; text-indent: -0.2in">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">-</span><span style="margin: 0px; font-size: 7pt"> </span><span style="margin: 0px; font-family: Arial; font-size: 12pt">Demo et al. �</span><a href="https://elifesciences.org/articles/28560" target="_blank" rel="noopener noreferrer" style="margin: 0px; color: purple; text-decoration: underline"><span style="margin: 0px; font-family: Arial; font-size: 12pt">Structure
of RNA polymerase bound to ribosomal 30S subunit</span></a><span style="margin: 0px; font-family: Arial; font-size: 12pt">�.<span style="margin: 0px"> </span><i>eLife</i>. 2017.</span><span style="margin: 0px; font-size: 12pt"></span></p>
<p style="margin: 6pt 0in 0.0001pt 23.75pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"; text-indent: -0.2in">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">-</span><span style="margin: 0px; font-size: 7pt"> <span style="margin: 0px"> </span></span><span style="margin: 0px; font-family: Arial; font-size: 12pt">Abeyrathne et al. �</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896748/" target="_blank" rel="noopener noreferrer" style="margin: 0px; color: purple; text-decoration: underline"><span style="margin: 0px; font-family: Arial; font-size: 12pt">Ensemble
cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome</span></a><span style="margin: 0px; font-family: Arial; font-size: 12pt">�.<span style="margin: 0px"> </span><i>eLife</i>. 2016.</span></p>
<p style="margin: 6pt 0in 0.0001pt 23.75pt; line-height: normal; font-size: 11pt; font-family: "Times New Roman"; text-indent: -0.2in">
<span style="margin: 0px; font-family: Arial; font-size: 12pt">-</span><span style="margin: 0px; font-size: 7pt"> <span style="margin: 0px"> </span></span><span style="margin: 0px; font-family: Arial; font-size: 12pt">Loveland et al. �<a href="https://elifesciences.org/articles/17029" target="_blank" rel="noopener noreferrer" style="margin: 0px; color: purple; text-decoration: underline">Ribosome�RelA
structures reveal the mechanism of stringent response activation</a>�.<span style="margin: 0px"> </span><i>eLife</i>. 2016.</span></p>
</div>
<div style="margin: 0px; font-family: "Segoe UI", "Segoe UI Web (West European)", "Segoe UI", -apple-system, BlinkMacSystemFont, Roboto, "Helvetica Neue", sans-serif; font-size: 15px; color: rgb(32, 31, 30); caret-color: rgb(32, 31, 30)">
<div style="margin: 0px; font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0)">
<br>
</div>
</div>
<br>
<br>
</div>
<div>
<div style="font-family: Calibri, Arial, Helvetica, sans-serif; font-size: 12pt; color: rgb(0, 0, 0);">
<br>
</div>
<div id="Signature">
<div style="font-family:Tahoma; font-size:13px">
<div style="font-family:Tahoma; font-size:13px">---<br>
Anna Loveland, Ph.D.<br>
anna.loveland@umassmed.edu<br>
617 610 4321 (cell)<br>
<br>
<font face="Tahoma" color="black" size="2"><span dir="ltr" style="font-size:10pt"><font size="1"><span style="font-size:13px">
<div>
<div style="margin:0"><font face="Segoe UI,Helvetica,Arial,sans-serif"><font face="Times New Roman,serif" size="3"><span style="font-size:12pt"><i><u>Confidentiality Notice:</u></i></span></font></font></div>
<div style="margin:0"><font face="Segoe UI,Helvetica,Arial,sans-serif"><font face="Times New Roman,serif" size="3"><span style="font-size:12pt"><i>This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain
confidential, proprietary and privileged information. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, please contact the sender immediately and destroy or permanently delete all copies of the original
message.</i></span></font></font></div>
</div>
</span></font></span></font><br>
</div>
</div>
</div>
</div>
</body>
</html>