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Hello all,
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<div class="">I was wondering what would be current best protocols for trying to improve maps/phases for low resolution
<div class="">MR / refinement solutions (5-6 Å resolution). </div>
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<div class="">High solvent content of course, dimeric 2:2 protein complex so some NCS averaging and density modification</div>
<div class="">I assume might help (related structures known, currently maps very blobby, clear solution but I think should be able to do better...).</div>
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<div class="">Also, refinement suggestions welcome.</div>
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<div class="">Best route in phenix? So far worked initially with ccp4. Other suggestions also welcome.</div>
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<div class="">Thanks!</div>
<div class="">Tommi</div>
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<div>Tommi Kajander, Ph.D. <br class="">
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<div>Institute of Biotechnology<br class="">
University of Helsinki<br class="">
Viikinkaari 1 (P.O. Box 65)<br class="">
00014 Helsinki, Finland<br class="">
p. +358-50-4480991<br class="">
<a href="http://www.helsinki.fi/kajanderlab" class="">http://www.helsinki.fi/kajanderlab</a></div>
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