<div dir="ltr"><p style="margin:0in"><font face="arial, sans-serif" style="">Dear Colleagues,</font></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<p style="margin:0in"><font face="arial, sans-serif">The Phenix developers will be holding a
day-long satellite workshop on July 29th, prior
to the ACA meeting in Portland, Oregon. This Phenix
user workshop will focus on using predicted models for crystallography
and cryo-EM</font></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<p style="margin:0in"><font face="arial, sans-serif">The
format of the workshop will be demos of the use
of Phenix programs combined with slides to explain the theory. We
expect an interactive meeting where attendees can ask questions for
the Phenix team to answer. </font><span style="font-family:arial,sans-serif">Topics will
cover aspects of macromolecular structure determination in Phenix.</span></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<p style="margin:0in"><font face="arial, sans-serif">For registration, see
the ACA 2022 website: <a href="https://www.acameeting.com/aca-wk2">https://www.acameeting.com/aca-wk2</a> .</font></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<p style="margin:0in"><font face="arial, sans-serif">Lecturers: Pavel
Afonine, Dorothee Liebschner, Billy Poon, Tom Terwilliger</font></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<p style="margin:0in"><font face="arial, sans-serif" style="">Looking forward to seeing
you there!</font></p><p style="margin:0in"><font face="arial, sans-serif" style=""><br></font></p><p style="margin:0in"><font face="arial, sans-serif" style="">The Phenix team</font></p>
<p style="margin:0in;font-family:Arial;font-size:11pt"><br></p>
<p style="margin:0in;font-family:Arial;font-size:11pt"> </p>
<p style="margin:0in"><font face="arial, sans-serif">Detailed Program:</font></p>
<p style="margin:0in"><font face="arial, sans-serif"> </font></p>
<div style="direction:ltr">
<table border="1" cellpadding="0" cellspacing="0" valign="top" style="direction:ltr;border-collapse:collapse;border-style:solid;border-color:rgb(163,163,163);border-width:1pt" title="" summary="">
<tbody><tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">8:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Welcome:
Introduction to Phenix, Introduction to the GUI, set up Phenix</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">8:45</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Overview
-- Strategy for X-ray or Cryo-EM structure determination using AlphaFold
models (lecture)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">9:15</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Predicting
your structure with AlphaFold and trimming it with ProcessPredictedModel
(demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">9:45</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Solving
an X-ray structure automatically by MR with PredictAndBuild (demo with
pre-computed data)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">10:15</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Break</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">10:45</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Evaluating X-ray
data with Xtriage</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">11:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Xray
refinement (lecture)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">11:30</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Xray
refinement with AlphaFold reference models (demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">12:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Lunch</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">13:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Ligands (lecture
& demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">13:30</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Cryo-EM
Data evaluation with Mtriage (short lecture & demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">13:45</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.4229in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Cryo-EM
map manipulations, map improvement with LocalAnisoSharpen and ResolveCryoEM
(demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">14:30</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;background-color:rgb(243,243,243);vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Break</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">15:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Automatic
cryo-EM map interpretation with PredictAndBuild (demo with pre-computed data)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">15:30</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Cryo-EM
refinement (lecture and demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">16:00</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Model
validation (lecture & demo)</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">16:30</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">Q&A</font></p>
</td>
</tr>
<tr>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:0.6673in;padding:4pt">
<p style="margin:0in;text-align:center"><font face="arial, sans-serif">16:50</font></p>
</td>
<td style="border-style:solid;border-color:rgb(163,163,163);border-width:1pt;vertical-align:top;width:6.3534in;padding:4pt">
<p style="margin:0in"><font face="arial, sans-serif">finish:
workshop survey and wrap up</font></p>
</td>
</tr>
</tbody></table>
</div><div><br></div>-- <br><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"><div>Research Scientist, Molecular Biophysics and Integrated Bioimaging<br></div><div>Lawrence Berkeley National Laboratory</div><div>1 Cyclotron Road, M/S 33R0345</div><div>Berkeley, CA 94720</div><div>Tel: (510) 486-5709</div><div>Fax: (510) 486-5909</div><div>Web: <a href="https://phenix-online.org/" style="color:rgb(17,85,204)" target="_blank">https://phenix-online.org</a></div></div></div></div>