Greetings PhenixBB,
I have a question that keeps coming up again and again. If I have a
part of my structure that is a blob of density and I have a map of what
that density cloud looks like, is there any way in phenix to include
that blob as part of the refinement? Perhaps giving it its own scale
and B factor? One example might be a user-defined bulk solvent map, but
a disordered ligand or domain can also come up. Traditionally, in older
refinement programs this was called a "partial structure", and it is a
feature still supported in refmac5. You give it "FPART=F PHIP=P" in the
input mtz file.
Last I checked there was no way to do this in phenix. Is that still
true? Any recommended ways to do things like this?
Thanks for your help and insight,
-James Holton
MAD Scientist
