Hi guys,<div><br></div><div>I was trying out the new Parallel Phaser (dev-1214) and using a model prepared by Rosetta covering 25% of the total structure (32% identity to the homology model), NCS = 2. 5 models actually but not really relevant since the program spontaneously stopped running after a couple of hours (I love what it&#39;s supposed to do though!). My question is about the log however. In the Parallel Phaser log it says:</div>
<div><div><font face="courier new, monospace">   Expected LLG and Resolution Limits</font></div><div><font face="courier new, monospace">   ----------------------------------</font></div><div><font face="courier new, monospace">   Expected LLG target:              120.00</font></div>
<div><font face="courier new, monospace">   Expected LLG achieved:            120.0</font></div><div><font face="courier new, monospace">   Resolution of All Data:            2.38</font></div><div><font face="courier new, monospace">   Resolution limited by eLLG target: 4.83</font></div>
<div><font face="courier new, monospace">      This resolution WILL NOT be used as the default</font></div><div><font face="courier new, monospace"><br></font></div><div><font face="courier new, monospace">   The expected LLG achieved is greater than 120 (eLLG target)</font></div>
<div><br></div><div>but when I tried to recreate that run in the regular Phaser-MR I get this message in the log</div><div><div><font face="courier new, monospace">   Expected LLG and Resolution Limits</font></div><div><font face="courier new, monospace">   ----------------------------------</font></div>
<div><font face="courier new, monospace">   Expected LLG target:              120.00</font></div><div><font face="courier new, monospace">   Expected LLG achieved:            49.7</font></div><div><font face="courier new, monospace">   Resolution of All Data:            2.38</font></div>
<div><font face="courier new, monospace">   Resolution limited by eLLG target: 2.38</font></div><div><font face="courier new, monospace">      This resolution WILL NOT be used as the default</font></div><div><br></div><div>
   The expected LLG achieved is less than 60 (half eLLG target)</div><div>      FTF rescoring WILL be performed due to low expected LLG signal</div><div>      Deep search will be performed from the start</div></div><div><br>
</div><div>I think the second result looks more realistic (unfortunately) but I still don&#39;t understand why the difference?</div><div><br></div><div>Cheers,</div><div>Morten</div><div><br></div><div>PS Seems like there&#39;s a memory leak in 1214 and 1207 when I run the Phaser step of MR_Rosetta. Does this sound right? Definitely in 1207 but it seems like it&#39;s still there in 1214.</div>
<div><br></div>-- <br>Morten K Grøftehauge, PhD <div>Pohl Group</div><div>Durham University</div><br>
</div>