For those of you trying out density modification for cryo-EM (phenix.resolve_cryo_em), the automatic estimation of resolution in the current version uses unmasked resolution instead of masked, in some cases resulting in running density modification at too low a resolution.

Consequently it is best with this version if you specify your nominal resolution.  To run it you can type:

phenix.resolve_cryo_em half_map_1.ccp4 half_map_2.ccp4 \

   seq_file=seq.dat resolution=3.5

or something like that.  It requires the current nightly build to run.

You might also want to wait just a short while and a version that has this and a few other bugs fixed, a GUI, full documentation, and an example dataset will be out (hopefully this week).

The full description of the method is at https://www.biorxiv.org/content/10.1101/845032v1

Let me know of any problems or suggestions!

All the best,

Tom T
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