Hi Structural biologist colleagues!  

Our article that helps you make the case that the experiment is still very much needed is now out:

https://www.nature.com/articles/s41592-023-02087-4

"AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination."  Nature Methods (2023)

Also, here is a video on the Phenix Tutorials YouTube channel that describes this analysis:  https://www.youtube.com/watch?v=ugMPYdPo8Bc

(I hope you will be happy to see that you and your structural biology colleagues get the credit for making AlphaFold possible at 2:35 in the introduction of this video!  Keep up the fantastic structural biology work!)

All the best,
Tom T
--
Thomas C Terwilliger
Laboratory Fellow, Los Alamos National Laboratory
Senior Scientist, New Mexico Consortium
100 Entrada Dr, Los Alamos, NM 87544
Tel: 505-431-0010