Hi Hailiang,
I was trying to do a B-factor sharpening using phenix GUI CreatMaps utilities. The output for the sharpened maps contains 2FOFCWT and PHI2FOFCWT columes, so I think they are sigmaA weighted 2Fo-Fc maps.
there is no need to guess. If you look at the "Map type" filed it will tell you which map you computed. Looking right now: "Map type" says "2mFo-DFc", and the corresponding labels are 2FOFCWT, PH2FOFCWT. So the answer: yes, what you get is the maximum-likelihood weighted map.
But from Brunger's paper, the sharpening coefficients seems directly applied on Fo, and I wonder what happened before we get the 2mFoDFc maps. Or, the sharpening coefficients have been applied to the 2mFoDFc maps?
I do not remember what's in that paper, my vague recollection is that the exp(B*s**2) is applied to F=map_coefficients. Anyway, in PHENIX the exp B-sharpening applied to the map coefficients (not to Fobs). You have two options here: provide your own B-factor to be used for sharpening or let PHENIX determine it automatically. Pavel.