![](https://secure.gravatar.com/avatar/d80a7424647283927ed45028a8486597.jpg?s=120&d=mm&r=g)
30 Aug
2009
30 Aug
'09
5:05 p.m.
Hello all, I try to solve the structure of a big complex at rather low resolution. I have a molecular replacement solution with a partial model from Phaser. I would like to use RESOLVE for density modification. I ask for your advice regarding the first map that should be the input into RESOLVE. Should it be the 2mFo-DFc map directly from Phaser or would it be better to do rigid body refinement in phenix.refine and use the bulk solvent corrected 2mFo-DFc map ? Many thanks in advance for your suggestions, Peter.