7 Oct
2009
7 Oct
'09
12:30 a.m.
I suspect that negative peaks are from the bulk-solvent mask, as you suspected.
The bulk solvent is flat... at least phenix.refine uses Flat Bulk solvent model (mask based). If bulk solvent is guilty for this, why would you observe peaks ? I repeat once again: looking at Average Kick map may resolve this puzzle. Pavel.