Actually Simone, I just found that my problem has already been reported (I’m on 10.13.6):

> Currently, there is an issue with using phenix.rosetta_refine and macOS High Sierra (10.13).
> The rosetta.run_tests step in the installation instructions is generating large files and using large amounts of memory.

so it’s apparently a Mac-specific issue and cannot also be the cause of your RuntimeError... 

Begin forwarded message:

From: Luca Jovine <[email protected]>
Subject: Re: [phenixbb] Rosetta installation problems
Date: 6 October 2018 at 15:05:50 CEST
To: "[email protected]" <[email protected]>

I don’t think the two things are related, but - when running under Mac OS the refinement tests of Rosetta (3.9 = 2018.09.60072) with PHENIX 1.14-3260 - I am also getting a (different) RuntimeError. The same test suite worked just fine with 1.13, so maybe there’s some general Rosetta compatibility issue with 1.14?
Best, Luca