Re: [phenixbb] Are sigma cutoffs for R-free reflections cheating?

Hi Ed,

You are essentially asking for proof that all the experimental data must be included while fitting theoretical model to it.

No, of course. I was just wondering how better (and what is "better" in this case) the refinement results will be if one includes the negative (zero) reflections into the process of refinement, and did anyone clearly demonstrate it. That's all I asked. Again, I hardly believe that you will notice the difference in refinement outcome (refiened model) if phenix.refine removes a few zero reflections that are in your PDB file. But I might be wrong and so wrote my previous question. Pavel.