Re: [phenixbb] Refining with NCS

Hi Francis,

Also if anyone has a paper/protocol for NCS refinement, I'd love to check it out (to figure out which map to fit to).

Just something to keep in mind... I always prefer to run two refinements in parallel with and without using NCS. It's resolution (and data-to-parameters ratio) dependent. I've seen a number of cases where using the NCS is very beneficial and similar number of cases where it's better to not use NCS (mostly at resolutions ~2-2.5A). I would also check manually the NCS groups that are found by phenix.refine automatically. I have some cases where automatic detection did not yield a good selection. Pavel.