Hi Scott,


"I am currently assuming that the histogram matching does not use model building as part of it, and would like to know if this interpretation is correct.​"


Yes, that is correct. The histogram matching part of resolve density modification does not require model-building.  However if you use build=true then some density modification steps will indeed use the model-based information as part of the density modification target.


All the best,

Tom T



From: [email protected] <[email protected]> on behalf of Scott Horowitz <[email protected]>
Sent: Thursday, December 10, 2015 8:51 AM
To: PHENIX user mailing list
Subject: [phenixbb] autosolve density modification question
 
Hi, a quick question: if when running autosolve on SAD data, if I set the parameter build = false, will that disable all model building, including any model building that would be a part of the density modification process? I'm especially curious about  the case if build = false, but mask_type = histograms. I am currently assuming that the histogram matching does not use model building as part of it, and would like to know if this interpretation is correct.

Thanks,
Scott

--
Scott Horowitz, Ph.D.
Research Associate
Howard Hughes Medical Institute

University of Michigan
Department of Molecular, Cellular, and Developmental Biology
Bardwell lab
830 N. University Ave, Room 4007
Ann Arbor, MI 48109
phone: 734-647-6683
fax: 734-615-4226