I used elbow to generate restraints for taxol using chemical componenet and sdf file. I posted before to the list and Oleg was kind enough to provide restraints generated by readyset. No matter what restraints I use, the taxol is messed up!

The other thing is, the refinement keeps breaking the peptide bond at a specific location! I would like to send some files to someone privately to investigate!

Please let me know.

Regards.