Re: [phenixbb] on Rwork and Rfree

On Mon, Feb 6, 2012 at 5:39 PM, Dialing Pretty wrote:

I did a Phenix refine,Rwork increases from 0.2366 to 0.2455, Rfree increases from 0.2363 to 0.2668, but the Molprobity analysis results were pretty satisfactory.

Do you think whether my results are reliable or not?

Definitely not (it's almost never a good sign when R-free increases), but how did you start with an R-free lower than R-work? -Nat