7 Dec
2012
7 Dec
'12
10:17 p.m.
On Fri, Dec 7, 2012 at 1:54 PM, Douglas Theobald
Maybe I've misunderstood, but Karplus and Diederichs used phenix in their paper arguing for including weak data. Whether the benefit they describe is considered cosmetic or non-trivial, it at least appears that including very weak data doesn't hurt. At least with phenix.
Yes, I forgot to mention this. I suspect that most other modern refinement programs, which all use maximum likelihood targets (but with various differences), would behave similarly. -Nat