I&#39;m new to phenix and just installed Phenix 1.3 beta rc6.&nbsp; <br><br>I&#39;ve taken a data set that I&#39;ve been refining in cns and am trying phenix.refine.&nbsp; The data has a twinning fraction of 0.5.&nbsp; I&#39;m seeing what I think is odd in the 2mFobs-DFmodel.map.&nbsp; If I&#39;m reading the documentation correctly, this map should be detwinned (I also set refinement.twinning.detwin.map_types.aniso_correct=true), I see alot of extra density where there is no model, nor a symmetry related molecule in coot.&nbsp; I don&#39;t see this extra density in my detwinned 2fofc cns maps.&nbsp; <br>
<br>So, could the extra density I&#39;m seeing be due to using a different program and it is detwinning the data differently.&nbsp; The extra density is from the twin????<br><br>Any input would be appreciated,<br><br>Mary X. Fitzgerald<br>
Postdoctoral Associate<br>Arnold Lab<br><br>