We are excited to announce the release of CryoFIT, a program for fitting atomistic models to cryo-EM maps. The current version is designed for fitting lower resolution maps but this does not preclude use with higher resolution maps. The CryoFIT modules is built on Gromacs and accessible through Phenix (
https://www.phenix-online.org/documentation/reference/cryo_fit.html), currently via GitHub. It supports both the Phenix GUI and the command line. CryoFIT is based on the algorithm in Kirmiziatltin, et al., Methods of Enzymology 2015 (
https://doi.org/10.1016/bs.mie.2015.02.011). This is an alpha version. Please send any feature requests and bug reports to Doo Nam Kim (
doonam@lanl.gov).