Re: [phenixbb] Fo-Fc omit map for ligand in the protein-ligand structure

I don't believe I said he was the first. He did develop an implementation which has proven useful to a large number of people. Dale On 9/16/2014 8:52 PM, Nathaniel Echols wrote:

On Tue, Sep 16, 2014 at 11:36 AM, Dale Tronrud mailto:[email protected]> wrote:

This sounds like Bricogne's maximum entropy maps.

Maybe I'm misunderstanding this reference, but I don't think Bricogne was the first person to come up with the idea:

https://www.researchgate.net/publication/232761305_Electron_density_images_f...

which I think is just an extension of the application to X-ray astronomy described by Gull & Daniel (1978).

-Nat