Re: [phenixbb] How to fix atoms in refinement

Hi Raj,

Hi, I have flexible a flexible loop in my structure and every time i refine it derange ramachandrans. Can anyone suggest how can i fix these flexible residues in phenix refinement so basically i don't wanna refine them. Can i do this in GUI?

Refinement settings -> Modify selections for (XYZ coordinates, this is the default) -> Edit then enter atom selections, (example: chain A and resseq 12:15) Alternatively you can apply Ramachandran plot restraints selectively to these loops. Also, doing weights optimization may be helpful too. Pavel