Dear Phenix users,<br><br>I have a very anisotropic data as phaser reports anisotropic deltaB = 60.2. I would be grateful for advice of several issues.<br>1.Could you please tell me if phaser map coefficients FWT,PHWT take into account the anisotropic scaling ?<br>
2.This means that these coefficients will be different from those calculated from a partial model in sigmaa because sigmaa has no anisotropic scaling (and no bulk solvent correction) ?<br>3.In the case of such severe anisotropy can the scaling diminish too strongly the well measured high resolution reflections ? If so should I calculate the coefficients my self by sigmaa and not use pahser mtz output or is there a better solution ?  <br>
<br>Many thanks in advance for sharing your thoughts and experience,<br><br>Peter.<br><br>