Re: [phenixbb] on Bulk-solvent and scaling

Will you please introduce to me briefly on the function of the step of Bulk-solvent and scaling in the Phenix refine and what is the corresponding mechanism?

Bulk-solvent and overall scaling revisited: faster calculations, improved results. Afonine PV, Grosse-Kunstleve RW, Adams PD, Urzhumtsev A. Acta Cryst. D69, 625-34 (2013). http://journals.iucr.org/d/issues/2013/04/00/dz5273/dz5273.pdf