With apologies for duplicate postings:


The biannual Gordon Conference on Diffraction Methods in Structural Biology will be held at Bates College in Lewiston, Maine from 18-23rd July. The program covers all aspects of macromolecular structure solution from crystallization to structure solution and refinement and includes sessions on complementary techniques and the potential of free electron lasers. Many of the leading methods developers will be present and the format of the meeting, with free afternoons, provides ample opportunities for informal discussions.

Further details, including a full program and details on the application procedure can be obtained from:

http://www.grc.org/programs.aspx?year=2010&program=diffrac

We hope to see you there !

Andrew Leslie (Chair) & Ana Gonzalez (Vice Chair)


Outline Program:

Sunday pm: Macromolecular Structures, Pushing the boundaries

Discussion leader: Michael Rossmann

 1. ABC Transporters: Doug Rees

 2.  The Spliceosome : Kyoshi Nagai

 

Monday am:  Crystallisation and the diffraction experiment

Discussion leader: Zbyszek Dauter

 1. Nanolitre crystallisation:  Seth Harris

 2.  Twinning and disorder: Todd Yeates

 3. Simulating the diffraction experiment: James Holton

 4. Microcrystallography:  Gwyndaf Evans

 

Monday pm: Radiation damage and data collection strategies

Discussion leader: Vivian Stojanoff

 1. Radiation damage, experimental: Elspeth Garman

 2.  Microbeams: Yanhui Zou

 3. Testing data collection strategies with the Pilatus: Marcus Mueller

 

Tues am: Synchrotron developments and automated data processing

Discussion leader: Thomas Schneider

 1. Synchrotrons, latest developments: Sean Mc Sweeney

 2. Synchrotrons, latest developments:  Janet Smith

 3. Data processing with Xia2/CHEF: Graeme Winter

 4. Data processing with AUTOPROC: Clemens Vonrhein

 

Tues pm:  Complementary techniques

Discussion leader: Ana Gonzales

 1. Electron tomography: Sriram Subramaniam

 2. SAXS: Hiro Tsuruta

 3. Spectroscopy: Carrie Wilmot

 

Weds am: Structure solution and refinement

Discussion leader:  Paul Adams

 1. SAD Phasing: Randy Read

 2. Molecular replacement with BALBES: Garib Murshudov

 3. PHENIX: Tom Terwilliger

 4. TLS: Ethan Merritt

 

Weds pm:  Challenging problems/Membrane Proteins

Discussion leader: TBC

 1. Using cubic lipidic phase: Martin Caffrey

 2. Membrane Proteins: Stephen White

 3. The Bacterial Ribosome: Venki Ramakrishnan

 

Thurs am:  Selected Posters and Map improvement and Model building

Discussion leader: Tassos Perrakis

 1. COOT: Paul Emsley

 2. Modelling nucleic acids: Johan Hattne

 

Thursday pm: Future Methods, FELs, Diffraction imaging

Discussion leader:  Ed Lattman

 1.  Anton Barty

2.  Serial Crystallography: John Spence and Petra Fromme