Postdoctoral position open at the University of Massachusetts Medical School, in the Korostelev Lab: https://www.umassmed.edu/korostelev-lab/.

We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in: (1) Translation accuracy; (2) Ribosome's central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some lab publications are provided below.

 

Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: https://www.umassmed.edu/rti/about-the-rti/faculty-members/. Our colleagues are interested in nearly all aspects of RNA biology, from small to large RNAs to RNA chemistry and therapeutics development.


We seek a highly motivated person who very recently received a PhD, or will soon receive a PhD.  Applications sent prior to the dissertation defense date are welcome.

Please submit the following information via email to: [email protected]

1)            your CV (including publication list);
2)            in less than 2 pages, an outline of your: 

     (i) previous work - focusing on your most interesting finding(s); 

     (ii) your current/future scientific interests, and whether/which aspects of translation regulation sound interesting to you;

3)             email addresses of three references.

 

Selected publications (accessible via the provided links):

-      Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation termination”. eLife.2019.

-      Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelity”. Nature. 2017.

-      Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunit”. eLife. 2017.

-       Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome”. eLife. 2016.

-       Loveland et al. “Ribosome•RelA structures reveal the mechanism of stringent response activation”. eLife. 2016.





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Anna Loveland, Ph.D.
[email protected]
617 610 4321 (cell)

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