Hi Pete, please have a look: http://www.phenix-online.org/presentations/fem_06MAY2014.pdf We are working on the manuscript too. Pavel
- phenix.fem (new command): - Compute "feature-enhanced" map ("FEM") - this protocol modifies a 2mFo-DFc sigmaA-weighted map such that the resulting map has strengthened weak signal, if present, and a reduced amount of noise and model bias. - combines randomization and averaging, treatment of missing reflections, residual composite omit map, and histogram equalization - resulting maps are more interpretable and have less bias compared to the starting 2mFo-DFc map - very fast procedure, no refinement required
Is there a citation for this, or a description of the method somewhere?