---------- Forwarded message ----------
From: "Rudenko, Gabrielle"
To: "[email protected]"
Date: Sat, 1 Mar 2014 20:36:00 +0000
Subject: Post-doctoral Fellowship at the University of Texas
* Macromolecular Crystallography, Biophysics and
Biochemistry*
A post-doctoral fellowship position is available at the University of Texas
Medical Branch (UTMB) located in the greater Houston area in the research
team of Dr. Gabrielle Rudenko. We study molecules that mediate the
formation, maintenance and plasticity of synapses, the contact and
communication point between neurons. Our proteins of interest organize and
regulate protein interaction networks in the synaptic cleft and impact how
neurons communicate with each other at synapses. Many of the proteins we
study are implicated in neurological disease and serve as potential novel
therapeutic targets.
We are looking for highly motivated, enthusiastic, hard working individuals
who are interested in combining the fields of structural biology and
neuroscience. Research projects involve protein over-expression and
purification, x-ray crystallography, biochemical and biophysical
techniques, proteomics, chemical biology and in collaboration electron
microscopy and NMR.
Our laboratory is part of the endowed Sealy Center for Structural Biology
and Molecular Biophysics and the Department of Pharmacology/Toxicology at
UTMB. The Sealy Center provides access to exceptional facilities, training
and experimental assistance. *X-ray facilities* include a high-brilliance
FR-E Superbright x-ray generator, a Rigaku R-AXIS-IV dual 30cm Imaging
Plate detector, a Bruker SMART 2K CCD and a Rigaku BioSAXS-1000 2D-Kratky
camera (for solution scattering data). *Biophysics facilities* include
equipment for analytical ultracentrifugation, fluorescence, MALDI-TOF mass
spectrometry, dynamic light scattering, surface plasmon resonance,
titration micro-calorimetry, and high throughput screening with the
ThermoFluor HTS apparatus. In addition, the *Electron Microscopy
facilities*house three modern JEOL cryo-electron microscopes (a 200
keV JEOL 2200FS
cryo-EM with in-column electron energy filter and field emission gun, a 200
keV JEOL 2100 EM, and a 120 keV JEM1400 microscope) and the *NMR
facilities*include three NMR spectrometers (Bruker Avance III 800, 750
and 600 MHz
with cryoprobes).
See http://www.scsb.utmb.edu/resources/
UTMB is part of the Texas Medical Center, the world's largest medical
center located in greater Houston. UTMB has research facilities situated on
Galveston Island offering a pleasant subtropical climate and miles of
relaxing beaches. UTMB is located within commuting distance of Houston, the
fourth largest city in the United States and a leader in the arts,
education, and health care.
*Qualifications:* Applicants should have received a Ph.D. degree in a field
relevant to structural biology within in the last three years and have a
strong publication record. Applicants with experience in cloning,
bacterial/insect cell culture, protein purification and crystallization,
and macromolecular structure determination are preferred. However, recent
graduates with a strong background in protein over-expression and
purification, and an exceptional interest in learning crystallography are
also encouraged to apply. Good written and oral communication skills in
English are essential as well as the ability and desire to work as part of
a highly motivated, collaborative team.
To apply please e-mail the following to
*[email protected]*:
CV, contact information for three references (address, phone and e-mail), a
list of your experimental expertise and skills relevant to this position
and a research statement describing your past research experience and
future goals (1-2 pages). Visa sponsorship is available for non-US
nationals. For questions, please contact Dr. Gabrielle Rudenko at
[email protected]
For more information please visit http://scsb.utmb.edu/labgroups/rudenko/
The University of Texas is a non-discriminatory, affirmative action
employer.
Gabrielle Rudenko, PhD
Dept of Pharmacology and Toxicology
Sealy Center for Structural Biology & Biophysics
University of Texas Medical Branch
301 University Boulevard
Basic Sciences Building Rm. 5.114B
Galveston Texas 77555
