Hi all,<br>I am new to structure solving. I have a 2.9A dataset for a
Seleno crystal of which i am trying to use Autosol to build an initial
map. I used the settings for a thorough solution, instead of quick. All
the other  parameters were set to default settings.<br>
The solution that i got from autosol, gave me the following result<br>Solution # 1  BAYES-CC: 23.7 +/- 30.9 Dataset #1   FOM: 0.27<br>Residues built: 238<br>  Side-chains built: 139<br>  Chains: 15<br>  Overall model-map correlation: 0.65<br>

  R/R-free: 0.38/0.42.<br>Score type:       SKEW    CORR_RMS<br>Raw scores:        0.02      0.77  <br>100x EST OF CC:   16.86     32.11  <br>The density modification map matches, quite well with many of my side chains fitted.<br>

<br>My question here is , IS THERE A WAY I CAN IMPROVE THE Figure Of Merit , BY CHANGING ANY PARAMETERS IN PHENIX-AUTOSOL. <br>I
HAVE A HIGH SOLVENT CONTENT IN MY CRYSTAL AND I DID NOT INPUT THAT IN
MY INITIAL PARAMETERS. DOES PHENIX AUTOSOL CONSIDER SOLVENT FLATTENING
FOR SUCH CRYSTALS?<br>
<br>I would appreciate someone&#39;s help in this regard<br><br>Thanks<br><br>Shankar