Dear all,<div><br></div><div>I have partially rebuilt my model after autosol and now I would like to submit it for refinement to Phenix refine.</div><div><br></div><div>However when I do so, even though the R factors go down when I have a look at the result, it just looks awful! All the model is placed out of the electron density map, plus the electron density map doesn&#39;t look anymore like a 3 A one, but just like sausages.</div><div><br></div><div>Why is this happening? The truth is I have no idea...</div><div><br></div><div>What I do is to provide Phenix refine with overall_best_refine_data.mtz (coming from autosol) as phases, x Ray data and x Ray r free data. Additionally, the starting model and the sequence.</div><div><br></div><div>Any suggestions are more than welcome.</div><div><br></div><div>Thanks a lot in advance.</div><div><br></div><div>Best wishes,</div><div><br></div><div>Almudena<br><br></div><br><br>-- <br><div dir="ltr">Almudena Ponce-Salvatierra<div>Macromolecular crystallography and Nucleic acid chemistry</div><div>Max Planck Institute for Biophysical Chemistry</div><div>Am Fassberg 11 37077 Göttingen</div><div>Germany</div><div><br></div></div><br>