Hello PhenixBB,<br>
<div><br>We are interested in refining 3 distinct backbone conformations of a loop (A, B, C). Our crystals are very high resolution and the density is fairly distinct for each of these conformations.<br>
</div><div><br>In the simplest case - each individual backbone conformation has one residue in two alternative side chain conformations. (A1,A2; B1,B2; C1,C2).<br></div>
<br>We&#39;d like to keep each pair of conformations assigned to the respective loop and then refine all six occupancies.<br>
<br>Is there such an option similar to the free parameters in shelx also available in phenix?<br>
<br>Thanks,<br>Marcus